The Mechanism of Action of Methylcobalamin

The Mechanism of Action of Methylcobalamin

Methylcobalamin is an endogenous vitamin B12, but it is more easily absorbed by the body than vitamin B12 and has better conductivity for nerves, as can be seen from its name, which contains the metal element cobalt. When methylcobalamin enters the body it can work quickly to make the metabolism of folic and nucleic acids faster and improve the excitability and transmitter level of nerves, which is effective for the treatment of peripheral neuropathy. In addition, it does not need to be metabolized by the liver and can be directly decomposed and absorbed, so it does not produce toxic side effects on the liver.

Mechanism of action

Mecobalamin is endogenous vitamin B12, which exists in blood and medulla. Compared with vitamin B12, it has good improvement on neuronal conduction, can promote nucleic acid-protein-fat metabolism through methyl conversion reaction, and it acts as a coenzyme of methionine synthase, which can convert homocysteine to methionine, participate in the process of deoxynucleoside synthesis of thymine, promote nucleic acid and protein synthesis, and promote intra-axonal transport and axonal regeneration and myelin formation, prevent axonal degeneration, and repair damaged neural tissue. Vitamin B12 has important physiological functions for the human body, especially in maintaining the health of the nervous system and the health of blood cells.

Indications of Methylcobalamin

Megaloblastic anemia

The disease is mainly due to the lack of vitamin B12. Methylcobalamin can promote the proliferation of red blood cells, improve cell activity and make the number of cells larger, thus improving anemia. If you experience dizziness, panic attacks and pale lips for a long time, it is recommended that you check for vitamin B12 deficiency.

Peripheral neuropathy

Peripheral neuropathy is a sensory and motor disorder. If the sensory and motor nerves are impaired, the body will experience facial twitching, numbness in the hands and feet, uncoordinated limbs, no sweating, muscle atrophy and other symptoms. The function of methylcobalamin is to nourish the nerves, repair the damaged nerves, make the nerves conduct normally and relieve the above symptoms.

Side effects

It may cause a variety of intestinal reactions, such as nausea, regurgitation, acid reflux, diarrhea, etc. It may also lead to loss of appetite, inability to eat and weight loss. In fact, food also contains methylcobalamin. If you have already had adverse reactions to the drug, then it is recommended that you supplement vitamin B12 through diet, such as common meat, eggs, milk, etc. Patients can eat more, and do not be picky or partial.