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According to its action properties and half-life, sulfanilamide can be divided into systemic infection sulfanilamide, intestinal sulfanilamide and external sulfanilamide. Among them, sulfanilamide for systemic infection can be divided into short-acting sulfanilamide (half-life is about 6 hours), including sulfanilamide = methazine, sulfanilamide = methisopyrimidine, sulfanilamide isoxazole, etc. Intermediate-effect sulfanilamide (half-life about 12 hours), including sulfadiazine, sulfamethyloxazole, sulfabenzopyrazole, etc.; Long-acting sulfonamide (half-life more than 24 hours), including sulfamethoxypyrazine, sulfamethoxine, sulfamethoxine, sulfamethoxazine; Sulfamethoxylpyridazine, sulfamethoxylpyrimidine, etc. Intestinal sulfanilamide mainly plays a bacteriological role in the intestine, including sulfanilamide, suxisulfathiazole, phthalide sulfathiazole, phthalide sulfathiazole (sirami), salazine sulfapyridine and so on. The main topical sulfonamides are sodium sulfanilamide, methylsulfonate pus, silver sulfadiazine and so on.
Use of Sulfadimethoxine.
The antibacterial effect and clinical efficacy were similar to SD. The absorption is rapid and the excretion is slow, the effect is maintained for a long time, the acetylation rate in the body is low, and it is not easy to cause urinary tract damage. In addition to broad-spectrum antibacterial action, this product also has significant anti-coccidia and anti-toxoplasmosis action. It is mainly used for the prevention and treatment of coccidiosis of calves, chickens and rabbits, infectious rhinitis of chickens, avian cholera, leukocytoplasmosis of carinii, toxoplasmosis of pigs and dogs (often used in combination with pyrimidine) and nocardiosis of dogs and cats, and can also be used for the prevention and treatment of bacterial rot gill disease, erecting squamosis, fish vibriosis, eel red fin disease, and furunculosis of carp fish.
A sulfonamides antibiotic that blocks dihydrofolate synthesis by inhibiting dihydrofolate synthase. Mode of action: Inhibition of folate synthesis in prokaryotes. Antimicrobial spectrum: Gram-positive bacteria, Gram-negative bacteria, chlamydia resistance mechanism: changes in dihydrofolate synthase or folate synthesis alternative pathway.
Pharmacological Effect of Sulfadimethoxine.
Product Method of Bulk Sulfadimethoxine Powder.
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