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Hossein extract is the dried whole grass extract of Aristolochiaceae plant, the main active ingredient is the volatile oil, the oil contains eugenol methyl ether, euzanol, camphor ether, β-pinene, Hossein ether, Hossein ketone and so on. Volatile oil has a special aromatic odour, foreign countries have developed the use of spicenard as a building material moth-proof filler and anti-mosquito insect repellent raw materials.
Uses of Asarum Extract powder.
Hyssop extract has a variety of pharmacological effects including antipyretic, analgesic, sedative, central inhibition and local anaesthesia.
Dispelling wind and dispersing cold, clearing the orifices and relieving pain, warming the lungs and resolving drinks. It is used in treating wind-cold, headache, toothache, nasal congestion and nasal abyss, rheumatic paralysis, phlegm and cough.
Pharmacological Effect of Asarum Extract powder.
1.Sedative, analgesic effect of the volatile oil of Sinensis extract intraperitoneal injection has a significant central inhibitory effect, can significantly extend the sleep time caused by sodium thiopental in mice.
Volatile oil has analgesic effect on rabbits by gavage. Fine Xin decoction by gavage also has analgesic effect on mice, and sedative effect.
2. Antipyretic, anti-inflammatory effect of Sinensis extract volatile oil gavage on experimental rabbits fever has antipyretic effect, and make the normal animal body temperature down to below normal.
The antipyretic effect of volatile oil 0.5mg/kg is comparable to that of antipyrine 0.5g/kg. Intraperitoneal injection of volatile oil of Liaoxin can inhibit the formation of cotton ball granuloma in rats, and have a certain inhibitory effect on formaldehyde and egg white pedunculopathy in rats.
Histamine, prostaglandin E2 foot swelling has obvious inhibitory effect, can inhibit the leukocyte wandering reaction, and can make the thymus atrophy, reduce the content of vitamin C in the adrenal gland of normal rats.
3. The role of the cardiovascular system of the extract volatile oil of Hoshin on the isolated frog heart, a small dose of excitation, large doses of inhibition, and pause in diastole; the guinea pig isolated heart, can make the coronary artery flow increase, relaxation of isolated rabbits isolated aorta, so that the isolated rabbit ear perfusion flow reduction, prolonging the time of the mice normobaric hypoxia resistance, the volatile oil of Hoshin can also dilate the visceral blood vessels of the toad; anaesthesia to the dogs, cats, static injection can lower the blood pressure, but its decoction The decoction can lower the blood pressure of anaesthetised dogs and cats, but its decoction has the effect of raising the blood pressure of anaesthetised cats.
Fine octanol extract of rabbits, guinea pigs isolated heart has an excitatory effect, the emergence of positive inotropy and positive frequency, so that the dog left ventricular pump function and myocardial contractility significantly improved.
4. The effect on the respiratory system of Chinese fine octanol extract can counteract the respiratory depression caused by morphine, and the perfusion flow of isolated lungs first showed a transient decrease, and then continued to increase.
Methyl eugenol in the oil of fine octane has a significant relaxation effect on the isolated guinea pig trachea.
5.Antibacterial effect of fine octane alcohol infusion, volatile oil, etc. on Gram-positive bacteria, Bacillus subtilis and typhoid fever bacillus has an inhibitory effect; decoction of tuberculosis and typhoid fever bacillus has an inhibitory effect. The volatile oil of Hoshin has antibacterial effect on Aspergillus flavus, Aspergillus niger, Aspergillus cereus, Candida albicans and other fungi and moulds.
Characteristic of Bulk Asarum Extract powder.
More than 90 compounds, mainly alkenes, benzenes, alkanes, alcohols, ketones, esters, etc., have been identified from the volatile oils of more than 30 kinds of domestically produced Sinapis plants.
Methyl eugenol (methyleugenol) is the main ingredient in the volatile oil of Sinensis. Also contains safrole, 3,5-dimethoxytoluene (3,5-dimethoxytoluene), elemicin (elemicin), eucarvone (eucarvone), β-pinene, α-pinene, α-pinene, asarone and other components.
1. cis-Methylisoeugenol (cis-Methylisoeugenol): molecular formula C11H14O2, molecular weight 178.22.
Crystalline solid, mp.78℃~79℃.
2. Asarinin: synonym of Asarinin. Molecular formula C20H18O6, molecular weight 354.34. (-): mp. 121 ° C (ethanol), [α] D20-118.6 ° (chloroform). Soluble in boiling methanol, ethanol, chloroform, acetone and benzene.
Almost insoluble in water.
3. Sesamin: synonym of sesamin, sesquiterpene. Molecular formula C20H18O6, molecular weight 354.34. Needle-shaped crystals (ethanol), mp.122 ℃ ~ 123 ℃
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