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Sulfonamides can be divided into sulfonamides for systemic infections, enteric sulfonamides, and topical sulfonamides according to the nature of their action and the length of their half-life. Sulfonamides for systemic infections can be divided into short-acting sulfonamides (half-life of about 6 hours), including sulfadoxine=methylpyrimidine,sulfadoxine=methylisopyrimidine, sulfisoxazole, etc.; intermediate-acting sulfonamides (half-life of about 12 hours), including sulfadoxine-pyrimidine, sulfamethoxypyrimidine, sulfamethoxypyrimidines, sulfadoxine-dimethypyrimidine, sulfadoxine-pyrimidine, sulfadoxine-pyrimidines, sulfadoxazine, sulfadoxine-o-dimethypyrimidine, sulfadoxine-pyrimidine, sulfadoxine-o-diimethypyrimidine, and others. methoxypyridazine, sulphadoxine-o-dimethoxypyrimidine, and so on.
Sulfonamide for intestinal use mainly plays a bacteriostatic role in the intestinal tract, there are sulfadimethoxine, sulfosulfathiazole, phthalosulfathiazole, phthalosulfonylacetamide (restramil), laurozine sulfadiazine pyridine, and so on. Topical sulfonamides mainly include sulfacetamide sodium, methosulfamethoxazole, silver sulfadiazine and so on.
Uses and functions of sulfadimethoxine Powder.
The antibacterial effect and clinical efficacy are similar to that of SD. Internal absorption is rapid and excretion is slow, the effect is maintained for a long time, the rate of acetylation in vivo is low, and it is not easy to cause damage to the urinary tract. In addition to broad-spectrum antibacterial effect, this product also has significant anti-coccidial, anti-Toxoplasma gondii effect. It is mainly used for the prevention and treatment of coccidiosis in calves, chickens and rabbits, and is also used for the prevention and treatment of infectious rhinitis in chickens, avian cholera, Kashiwagi leukocytosis, toxoplasmosis in pigs and dogs (often combined with ethyl pyrimethamine), and nocardia in dogs and cats, and it can be used for the prevention and treatment of bacterial gill disease, erectile scales, vibrio disease in fishes, eel red-fin disease, and boils in carps, etc.
Adverse reactions include gastrointestinal reactions, teratogenic effects on renal impairment, and cross-sensitisation. Sulphonamides should not be combined with local anaesthetics.
Pharmacological Effects of sulfadimethoxine Powder.
Sulfonamides can be divided into sulfonamides for systemic infections, enteric sulfonamides, and topical sulfonamides according to the nature of their action and the length of their half-life. Sulfonamides for systemic infections can be divided into short-acting sulfonamides (half-life of about 6 hours), including sulfadiazine, sulfamethazine, sulfamethoxazole, sulfisoxazole, etc.; intermediate-acting sulfonamides (half-life of about 12 hours), including sulfadiazine, sulfamethoxazole, sulfamethoxazole, etc.; long-acting sulfonamides (half-life of more than 24 hours), including sulfamethoxazole, sulfamethoxazole, sulfamethazine, sulfadiazine; sulfamethoxazole, sulfamethoxine, sulfadoxine, sulfamethoxazine; sulfadoxine-p-methoxazine; sulfamethoxydiazide; sulfadoxopridazine; sulfamethoxine; sulfamethoxine-octopyridazine; sulfamethoxazine Sulfadimethoxine; Sulfamethoxypyridazine, Sulfadimethoxine, Sulfadimethoxine, Sulfadimethoxine, Sulfadimethoxine, and others.
Production method of sulfadimethoxine Powder.
Sulfonamide antibiotic that blocks dihydrofolate synthesis by inhibiting dihydrofolate synthase. Mode of action: Inhibits folate synthesis in prokaryotes. Antimicrobial spectrum: gram-positive, gram-negative, chlamydia Mechanism of resistance: alteration of dihydrofolate synthase or alternative pathways of folate synthesis.
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