Acetate Gossypol Raw Materials Acetate Gossypol Powder

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Acetate Gossypol Usage and Synthesis.

Gossypol acetate is a phenolic constituent isolated from cottonseed with antibacterial, antiviral, antitumour and antifertility properties. In the treatment of uterine and endometrial cancers, Cotton Phenol Acetate has an efficiency rate of 87.2 per cent and 90 per cent.

In addition, it is widely used in the treatment of endometriosis, fibroids, functional uterine bleeding and other uterine diseases, with an effective rate of up to 100%. The mechanism of action of Medroxyprogesterone Acetate is mainly through the effective regulation of the 1st messenger hormone of the signal transduction pathway.

However, there are some side effects associated with the use of Medroxyprogesterone Acetate, such as poor appetite, dry mouth, diarrhoea, drowsiness and weakness. The main problem is a decrease in blood potassium, and hypokalemia may occur in individual patients, requiring prompt oral or intravenous administration of potassium salts.

The mechanism of its occurrence has not been fully elucidated. In conclusion, Medroxyprogesterone acetate is an effective drug for the treatment of uterine diseases, but its side effects need to be noted when using it.

Uses of Acetate Gossypol.

Cotton Phenol Acetate has very important medical and industrial uses, in male birth control, treatment of menopausal women's diseases, anti-tuberculosis, anti-tumour and anti-virus, etc. have certain effects.

Refined Cotton Phenol Acetate was used as a male birth control drug at a dose of 20 mg orally per day, which significantly reduced sperm viability, and was proven to be a reliable male birth control drug after 9,000 people had taken it. Cotton Phenol Acetate in the treatment of certain gynaecological diseases also have significant efficacy, such as uterine fibroids, functional haemorrhage, endometriosis and the treatment of certain urological diseases, such as prostate hyperplasia, prostate cancer on the obvious efficacy.

Pharmacological Effect of Acetate Gossypol.

Cotton phenol has obvious inhibition of spermatogenesis, the main part of its action is more sensitive to cotton phenol spermatozoa and late spermatozoa cells, followed by all levels of spermatozoa, with the increase in the dose of cotton phenol, the testis of the damage and destruction of the role of the corresponding intensification, can further make the varicocele all kinds of sperm cells shed all the way to the total disappearance of the tubules, so that the lumen of the tubular cavity, most of the tubular cavity only a layer of the base of the tubular wall of support cells and residual small amount of spermatogenic cells and disorganisation. Most of the lumen is empty with only a layer of supporting cells at the base of the tubular wall and a small number of spermatogonia remaining, and they are not well arranged.

Cottonwood acetate has an inhibitory effect on steroid hormone receptors in the ovary and endometrium, myometrium, thus making the endometrium and myometrium obviously thinned, and the menstrual flow is reduced; high concentration of cottonwood phenol can be associated with cell growth enzymes or functional proteins, so that apoptosis, but will not induce cell malignant hyperplasia; Cottonwood acetate through the inhibition of renal medullary collaterals of the ascending branch of the thick section (Na - K - Cl-) joint transport system, so that the sodium potassium ion, chloride ion reabsorption is reduced. ion and chloride ion reabsorption is reduced, resulting in renal potassium excretion.

Adverse reaction of Bulk Acetate Gossypol Powder.

Hypokalaemia, muscle weakness, gastrointestinal reactions such as loss of appetite, nausea and vomiting, as well as palpitations and mild alterations in liver function; may cause menopausal symptoms of menopause, amenorrhoea, loss of libido, hot flushes, itchy skin, sweating, etc.

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