Raw Materials Tinospora Extract Powder

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Tinospora Extract Powder Usage and Synthesis.

Wide Tendon Vine Extract is from the vine of Chinese Green Cow Guts of the plant family Fangji, which has the effect of relaxing the tendons, dispelling wind and relieving pain, dispelling wind and removing dampness, relaxing the tendons and activating the collaterals, and is good at relaxing the tendons and relieving the constriction of the tendons and muscles.

It can be used to treat rheumatic paralysis, sciatica, lumbar muscle strain, contracture of tendons and muscles, bone fracture, bruises and other diseases. In addition, the extracts of Wide-set Vine can antagonise the drop in arterial blood pressure caused by intravenous endotoxin and can reduce pulmonary oedema caused by endotoxaemia on the increased permeability of pulmonary vascular wall.

Rattan components such as broad tendon vine are also added to Lin Huai En boot extract, which has the effect of opening the meridians and detoxifying the body.

Uses and functions of Tinospora Extract.

The main efficacy of the extract includes relaxing tendons and activating collaterals, dispelling wind and relieving pain, and can be used to treat rheumatic paralysis, sciatica, lumbar muscle strain, contracture of tendons and collaterals, bone fracture, bruises and other diseases.

In addition, the extract has antidiabetic activity, which can rapidly reduce the blood glucose level of fasting animals and improve the glucose tolerance of rats.

At the same time, the extract also has anti-tuberculosis activity, can be used for the treatment of tuberculosis and other diseases.

Pharmacological Effect of Tinospora Extract.

1.Anti-radiation effect

To accept 60Co γ-ray 6Gy irradiation caused by blood system damage in mice, given to the wide tendon vine different doses of ethanol extract gavage, the results found that compared with the control group, the wide tendon vine ethanol extract gavage administration group of mice with a better recovery of leukocytes, and the high, medium and low dose groups have a better protection of erythrocytes, platelets, bone marrow DNA, the effect of the dose-dependence. The effects were dose-dependent, indicating that the plant has a good protective effect against radiation-induced damage to the blood system.

The administration of ethanol extract of Radix Codonopsis can promote the recovery of bone marrow haematopoietic function after radiotherapy, which also indicates that it has a certain anti-radiation effect.

2.Anti-inflammatory effect

Gavage of the aqueous extract of Radix et Rhizoma Gastrodiae can reduce the swelling degree of the ears of mice caused by xylene and the swelling degree of the toes of mice caused by egg white (P<0.01), and the inhibition rate of swelling strengthens with the increase of the dose, which indicates that Radix et Rhizoma Gastrodiae has an anti-inflammatory effect on the swelling of mouse tissues in a dose-dependent manner.

3.Other effects

The extracts of C. kwangsiensis have significant antioxidant effects; the ethanol and n-butanol extracts of C. kwangsiensis have significant antileishmanial effects, and this effect is closely related to the body to play the function of immunomodulation; it has the effects of hepatoprotection, immune regulation and preventing cyclophosphamide-induced anaemia, etc., and the aqueous extracts of C. kwangsiensis have elevated the number of leukocytes in mice more than that in the heart of Cynanchum vulgare.

It is now known that the broad-banded vine contains quaternary ammonium alkaloids, which are anti-inflammatory, detoxification, antibacterial, analgesic, muscle relaxation, etc.; broad-banded vine contains steroidal ketones, which have the effect of preventing and controlling osteoporosis, and can inhibit the loss of calcium or promote the differentiation of osteoclasts to improve the osteoporosis caused by the obstruction of calcium loss or the formation of osteoclasts.

These chemical constituents and their efficacy are consistent with the rationale for the treatment of rheumatic paralysis and lumbar strain, but additional qualitative and quantitative identification tests and pharmacological studies are needed to ensure the efficacy of the constituents.

Extraction method of Bulk Tinospora Extract Powder.

1.polysaccharide extraction of polysaccharides of C. kwangsiensis was extracted and purified, the extraction temperature was 90℃, the extraction was 90min, the material-liquid ratio was 1:10 (m/V, g:mL), the extraction rate of crude polysaccharides of C. kwangsiensis was 3.94%, of which the content of reducing polysaccharides was 20.40%, and the content of proteins was 8.21%; the protein removal method TCA method was the most suitable for the purification of the crude polysaccharides of C. kwangsiensis, and it could remove 86.83% of proteins, the retention rate of reducing polysaccharides was 68.67%.Chemicalbook2. It could remove 86.83% of the protein, and the retention rate of reducing polysaccharide was 68.67%.

2. Total alkaloid extraction of total alkaloids of C. kwangsi is the best extraction process: C. kwangsi herbs hydrochloric acid-70% ethanol (1:100) extraction 3 times, each time 1 hour, solvent dosage of 8 times the amount.

3.Pharmacogenine hydrochloride, pamatin hydrochloride, berberine hydrochloride wide tendon vine herbs crushed 80 mesh, add 40 times the amount of hydrochloric acid - methanol (1:100) mixed solution, reflux extraction for 60min. add 40 times the amount of hydrochloric acid - methanol (1:100) mixed solution, reflux extraction for 60min.

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