Gabapentin CAS 60142-96-3 Raw Powder

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Gabapentin Powder Usage and Synthesis:

Gabapentin is a medication used to treat seizures, neuropathic pain, restless leg syndrome, and hot flashes. It is also sometimes used off-label to treat anxiety and mood disorders. Gabapentin works by binding to a specific type of calcium channel in the brain and nervous system, which helps to reduce the activity of certain neurotransmitters that cause seizures and pain. It is available in tablet, capsule, and liquid form and is typically taken two to three times daily. Common side effects include dizziness, drowsiness, and fatigue. Gabapentin is a prescription medication and should only be used under the supervision of a healthcare provider.

Gabapentin Powder can be used for neuralgia after herpes infection,Gabapentin CAS 60142-96-3 is a GABA analogue used for the treatment of epilepsy and neuralgia.Gabapentin Powder is used for epilepsy patients with limited seizures that cannot be satisfactorily controlled or tolerated by conventional anti-epileptic drugs,China Pharmaceutical Intermediates Gabapentin Powder Supplier specializing in the production of Gabapentin raw materials.

Applications of Gabapentin Powder :

Gabapentin can be used for post-herpetic neuralgia; For the adjunctive treatment of partial seizures with or without secondary systemic seizures in adults and children over 12 years of age. It can also be used for the adjuvant treatment of partial seizures in children aged 3 to 12 years. It is used as an additional treatment for patients with localized seizures that are not satisfactorily controlled or tolerated by conventional antiepileptics, and for patients with localized seizures and subsequent generalized seizures. Anti-anxiety medication.

Gabapentin capsule's role mainly has the following two points:

1. Postherpetic neuralgia, for the treatment of adult postherpetic neuralgia.

2. Epilepsy, adjuvant therapy for adults and children over 12 with or without secondary systemic seizures partial seizures can also be used for adjuvant therapy for children 3 to 12 years of age partial seizures.

Gabapentin is mainly eliminated from the systemic circulatory system by renal excretion in its original form, and its metabolism in human body is not obvious. The elimination half-life of gabapentin is 5 to 7 hours and does not vary with dose or multiple doses. The elimination rate constant of gabapentin, plasma clearance and renal clearance are directly proportional to creatinine clearance, and plasma clearance of gabapentin is decreased in elderly patients and patients with renal impairment, and gabapentin is clearly visible from plasma by hemodialysis. Gabapentin capsule can be anticonvulsive, inhibit epileptic seizure, can be cleared from plasma through hemodialysis, less side effects, good effect.

Elderly patients; Patients with renal insufficiency should adjust the dose. Gabapentin may develop anaphylaxis and angioedema on the first dose or at any time during treatment. Gabapentin can cause drowsiness and dizziness. In patients who are treated with antiepileptic drugs (AEDs) for any indication, antiepileptic drugs (including gabapentin) can increase the risk of suicidal thoughts or behaviors in patients. Gabapentin should be discontinued immediately if clinical symptoms of pancreatitis (persistent abdominal pain, nausea, repeated vomiting) occur.

Pharmacological Effect of Gabapentin Powder:

Pregabalin Powder is used for the treatment of peripheral neuralgia and adjuvant treatment of localized partial  seizures. Pregabalin CAS 148533-50-8 has a good therapeutic effect on epilepsy,  and pregabalin is an analogue of the neurotransmitter gamma-aminobutyric acid (GABA). Pregabalin is the first drug  approved in the United States and Europe for both types of pain. China Pregabalin Powder Supplier and Manufacturer  Supply High Quality Pregabalin Powder.

Gabapentin is structurally related to the neurotransmitter gamma-aminobutyric acid (GABA), but has no effect on GABA binding, uptake or degradation. Gabapentin is a GABA analogue used to treat epilepsy and neuralgia.

Gabapentin tablet is a drug mainly used for the treatment of localized seizures where conventional antiepileptic drugs do not achieve satisfactory results, but also for the treatment of localized seizures and subsequent generalized epilepsy patients.

Method of Preparing Gabapentin Powder:

Gabapentine was obtained by the reaction of 1, 1-cyclohexane-7, monomethyl acid (I), ethyl chloroformate dissolved in acetone containing triethylamine and sodium azide dissolved in water. The product (Ⅱ) was formed by reflux in 20% hydrochloric acid for 3h.

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