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Thiamine pyrophosphate is a white crystalline powder, which can be used in biochemical research. It is clinically used to treat arrhythmia, myocardial infarction, coma and other diseases.
Thiamine Pyrophosphate (TPP), a metabolite of vitamin B1, is a cofactor synthesized within the cytosolute and is essential for the maintenance of the activity of cytosolute transketolase and mitochondrial pyruvate, ketoglutarate and branched ketoate dehydrogenase. TPP can be used to evaluate the mechanism of deacidification in biological systems. TPP can also prevent hyperglycemia-induced retinopathy and desfluran-induced hepatotoxicity in rats.
Use of Cocarboxylase.
Thiamine pyrophosphate (TPP) is the coenzyme form of vitamin B1 ( thiamine) , is formed by phosphorylation. It participates in a variety of enzymatic reactions as a cofactor, especially plays a key role in glucose metabolism. Specifically, thiamine pyrophosphate is a cofactor of pyruvate dehydrogenase and α-ketoglutarate dehydrogenase. is involved in α-ketoacid decarboxylation, promotes the decomposition and oxidation of sugars, and provides the body with energy. In addition, it is involved in the process of protein metabolism, promotes the transport and metabolism of amino acids, as well as the synthesis and breakdown of proteins. thiamine pyriphosphate also plays an important role in the nervous system, can promote the synthesis and release of neurotransmitters, to maintain the normal function of the nervous system
Thiamine pyrophosphate is also a coenzyme of decarboxylase, involved in a variety of biochemical reactions in organisms, including but not limited to glucose metabolism, protein metabolism and nervous system function maintenance. These functions are essential for human health, thiamine pyrophosphate deficiency may lead to a range of health problems, beriberi, ischemic heart disease, stroke, etc. 2.
In addition, thiamine pyrophosphate is also widely used in the field of scientific research, as a scientific reagent and biological products, support a variety of biological research. Because of its important biological functions, thiamine pyrophosphate plays an irreplaceable role in medicine, biotechnology and scientific research.
Pharmacological Effect of Cocarboxylase.
Product Method of Bulk Cocarboxylase Powder.
Thiamine hydrochloride reacts with phosphoric acid and is treated with hydrochloric acid.
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