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Lidoca hydrochloride is a local anesthetic agent of medium effect amide. Used as a local anesthetic and antiarrhythmic drug. Mainly used for:
(1) Infiltration anesthesia, epidural anesthesia, surface anesthesia (including mucosal anesthesia during thoracoscopy or abdominal surgery) and nerve block.
(2) Treatment of premature ventricular beats and ventricular tachycardia after acute myocardial infarction (AMI), as well as digitalis poisoning, cardiac surgery, cardiac catheterization caused by ventricular arrhythmias, but usually ineffective for supraventricular arrhythmias.
Uses of Lidocaine hydrochloride.
Lidocaine hydrochloride has the characteristics of strong penetration, strong dispersion, quick effect, anesthetic efficacy is twice that of procaine, and toxicity is 1. The anesthetic effect can appear 5 minutes after administration, and the anesthetic effect can last 1 to 1.5 hours, 50% longer than procaine. After absorption, it can inhibit the central nervous system, inhibit ventricular automaticity, shorten the refractory period, and can be used to control ventricular tachycardia and treat arrhythmia symptoms such as premature ventricular beat, ventricular tachycardia and ventricular fibrillation. It is effective for heart disease or arrhythmia caused by cardiac glycosides, but not effective for supraventricular tachycardia. This product acts quickly, has a short duration, is ineffective orally, and is often administered intravenously.
Lidocarzine hydrochloride local anesthetics. After blood absorption or intravenous administration, the drug has obvious biphasic effect of excitatory and inhibitory on the central nervous system, and there can be no precursor excitement, analgesia and lethargy, and the pain threshold is increased when the blood concentration is low. As the dose increases, the effect or toxicity increases, and the subtoxic blood concentration has anticonvulsant effect.
Pharmacological action of Lidocaine hydrochloride.
Product Method of Bulk Lidocaine hydrochloride Powder.
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