Etravirine Raw Material Etravirine Powder

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Etravirine Raw Materials Usage and Synthesis

Factory Supply Purity 99% Etravirine Raw Material, High Quality Supply Etravirine Raw Powder Factory Supply Supply Etravirine Powder, Manufacturer of Supply Etravirine Raw Materials. Etravirine Powder is a non-nucleoside reverse transcriptase inhibitor (NNRTI), a drug used to treat HIV.

Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV.

Etravirine Raw Materials

Uses and functions of Etravirine Powder

Etravirine (TMC125), is highly potent against wild-type HIV-1, with an EC50 of 1.4 nM to 4.8 nM, and also exhibits some activity against HIV-2, with an EC50 of 3.5 μM.TMC125 also inhibits a range of HIV-1 M subunits and circulating recombinant forms, as well as O viruses.

Etravirine Raw Materials

Pharmacological Effects of Etravirine Raw Powder

Etravirine has a high genetic barrier to resistance development.

In the phase IIb trial, among multiple-treatment patients, including those infected with NNRTIs-resistant and protease inhibitor (PIs)-resistant viruses, TMC125 was active against existing NNRTIs-resistant HIV and was similarly tolerated to controls.

Etravirine Raw Powder

Production method of Raw Etravirine Powder

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