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Ferulic acid also has the potential to treat a variety of diseases such as cerebral infarction, coronary heart disease, angina pectoris, and thromboembolic vasculitis. Studies have shown that ferulic acid inhibits or reduces the proliferative activity of melanocytes, as well as inhibiting tyrosinase activity.
Ferulic acid can increase cerebral microcirculation by inhibiting thrombosis and reducing blood viscosity in ischaemic stroke treatment. Therefore, ferulic acid is a natural compound with a wide range of applications and has a huge market and development potential.
Uses of Ferulic Acid.
Ferulic acid has many health functions, such as scavenging free radicals, anti-thrombosis, antibacterial and anti-inflammatory, inhibiting tumours, preventing high blood pressure, heart disease, and enhancing sperm vitality, etc.; and its low toxicity is easy to be metabolised by the human body, and it can be used as a food preservative, which has a wide range of uses in food, medicine and other aspects.
In addition to the wide application of ferulic acid in medicine, some countries have approved its use as a food additive.
Japan has allowed the use of food antioxidants, the United States and some European countries allow the use of some of the higher amount of ferulic acid-containing herbs, coffee, vanilla beans, etc. as antioxidants.
Ferulic acid in the food industry is mainly used in the preparation of natural vanillin, antioxidants, preservatives, crosslinking agents and function promoters, etc.
Pharmacological effect of Ferulic Acid.
Ferulic acid has the effect of inhibiting platelet agglutination, expectoration, and inhibition of Mycobacterium tuberculosis. Clinically ferulic acid is mainly used in atherosclerosis, coronary heart disease, cerebrovascular, glomerular disease, pulmonary hypertension, diabetic vasculopathy, vasculitis and other vascular diseases such as adjuvant therapy as well as leukocyte and platelet reduction.
It can be used in the treatment of migraine and vascular headache. As a leukocyte-boosting drug, this drug also has the effect of enhancing haematopoietic function. Therefore Ferulic acid can also be used in the treatment of leukocytes and and thrombocytopenia.
Preparation of Bulk Ferulic Acid Powder.
(1)Extracted from plant materials with high ferulic acid content such as Angelica sinensis, vanilla bean, wheat bran and rice bran, and then obtained ferulic acid by alkaline hydrolysis or enzymatic method.
(2) Chemical synthesis: synthesised by Kno-evngael reaction using vanillin and malonic acid as raw materials.
(3) Biosynthesis method: Using some microorganisms, the precursor substances of ferulic acid are transformed to obtain ferulic acid.
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