Dihydrocapsaicin Raw Materials Dihydrocapsaicin Powder

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Dihydrocapsaicin Powder Usage and Synthesis.

Dihydrocapsaicin, one of the main capsaicinoids in chilli peppers, has antiseptic and disinfectant properties and can be used as a food preservative.

Meanwhile, recent studies have shown that capsaicin is able to inhibit the growth of Helicobacter pylori, and regular consumption of chilli peppers can prevent the development of many types of stomach cancer. In addition, dihydrocapsaicin can be used in the manufacture of medicines, such as for the treatment of neuropathic pain and muscle atrophy.

It should be noted that for people with sensitive bodies or weak gastrointestinal tracts, it is not advisable to consume spicy foods in excess.

Uses of Dihydrocapsaicin.

Dihydrocapsaicin is an active ingredient in chilli peppers with a variety of physiological functions. Firstly, dihydrocapsaicin has bactericidal and disinfectant properties and can be used as a food preservative.

Secondly, it has been found that dihydrocapsaicin can inhibit the growth of Helicobacter pylori, preventing and treating gastric ulcers. In addition, dihydrocapsaicin has the effect of weight loss and can promote fat metabolism and energy expenditure.

Also, dihydrocapsaicin reduces mortality from cardiovascular diseases, reducing the overall risk of death by 23%. In conclusion, dihydrocapsaicin has a variety of physiological functions, but different people have different physical and digestive functions, and should consume chilli peppers in moderation according to their own dietary habits and physical condition.

Pharmacological effect of Dihydrocapsaicin.

It has the effect of sterilisation and disinfection, and can be used as a food preservative. Used in medical treatment, it has strong and long-lasting anti-inflammatory and analgesic effects and antibacterial, anti-tumour effects; it can also promote gastrointestinal peristalsis and gastric secretion to help digestion.

Preparation of  Bulk Dihydrocapsaicin Powder.

1)Silica gel is used to load the column by wet method, the solvent for loading the column is petroleum ether, or a mixture of petroleum ether and ethyl acetate or acetone, and the silica gel is used as thin-layer chromatography silica gel H;

2) Pressurised equilibrium column for 2-10h, using nitrogen, carbon dioxide and other gases to pressurise, the pressurisation pressure was 0.02-0.3Mpa;

3) Capsaicin (content of 85-100%) dissolved by acetone mixing silica gel on the sample, capsaicin and mixing silica gel dosage of 1:2-5, capsaicin and column chromatography silica gel dosage of 1:80-200, for 1:100-150;

4) elute with a mixed solvent of petroleum ether and ethyl acetate or acetone (wherein petroleum ether/ethyl acetate = 5-9:3, 6-8:3, petroleum ether/acetone = 5-9:2, for 6-8:2), and collect the effluent in steps;

5) Qualitatively detect capsaicin in the effluent by paper chromatography;

6) high performance liquid chromatography (HPLC) analysis of the effluent containing capsaicin, combined with the same monomer capsaicin, dihydrocapsaicin effluent;

7) Recovery of solvent, respectively, to obtain capsaicin, dihydrocapsaicin.

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