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Apigenin is a natural compound with a variety of pharmacological effects and health functions. Studies have shown that apigenin has preventive and therapeutic effects on a variety of diseases such as cardiovascular disease, diabetes, arthritis and tumors. Apigenin also has antioxidant, antihypertensive, vasodilatory, atherosclerosis prevention and tumor inhibition effects.
However, due to the poor water solubility and low intestinal absorption of apigenin, its oral bioavailability and in vivo activity are low, which limits its application to some extent.
Uses of apigenin.
The flavonoid contained in apigenin is a plant flavonoid that has been found to inhibit cell proliferation by blocking the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appears to be associated with the induction of p53.
Inhibition of PMA-mediated tumor promotion through inhibition of protein kinase C and the resulting suppression of oncogene expression. Studies have also reported inhibition of topoisomerase i-catalyzed deoxyribonucleic acid reattachment and enhancement of gap junction intercellular communication.
Synthesis method of apigenin.
Product Method of Bulk apigenin Powder.
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