Factory price Pyridoxal 5'-phosphate monohydrate Raw materials powder

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Pyridoxal 5'-phosphate monohydrate powder Usage and Synthesis.

PLP is so important that it is involved in more than 140 PLP-dependent enzyme activities, accounting for about 4% of all classified activities. The versatility of PLP comes from its electrophilicity: PLP covalently binds to the substrate by forming an external aldimine at the beginning of the reaction, and then different types of carbon anion reaction intermediates can be stabilized by PLP through resonance effects.

This function of PLP is also called "electron trap". In addition to the electron absorption effect, since almost all PLP-dependent reactions generate cationic and anionic intermediates, acidic and basic groups that assist proton transfer are equally important.

Uses of Pyridoxal 5'-phosphate monohydrate.

Pyridoxal 5-phosphate is an organic synthesis intermediate and a pharmaceutical intermediate. It can be used as a biochemical reagent in laboratory organic synthesis processes and chemical pharmaceutical research and development processes.

Resolve resolution of Pyridoxal 5'-phosphate monohydrate.

A method for synthesizing pyridoxal phosphate comprises at least the following steps:

Step 1, using active manganese dioxide as a catalyst to oxidize pyridoxine hydrochloride to pyridoxal hydrochloride;

Step 2, subjecting the pyridoxal hydrochloride to a condensation reaction with N,N-dimethylethylenediamine to obtain a pyridoxal condensate;

Step 3, subjecting the pyridoxal condensate to a phosphate esterification reaction with polyphosphoric acid to prepare a crude pyridoxal phosphate.

Product Methods of Bulk Pyridoxal 5'-phosphate monohydrate powder.

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