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Geniposide is an iridoid glycoside compound, isogeniposide, dormerin glucoside dehydroxygeniposide. Pure white powder, specific curl [α]D20+7.5° (water). Soluble in water, soluble in ethanol, insoluble in petroleum ether. Gardenin has a variety of uses, different conditions of fermentation, can be made into natural food colorants gardenia blue and gardenia red, is also used for the treatment of cardiovascular and cerebrovascular diseases, liver and gallbladder diseases and diabetes raw materials.
Uses of Geniposide.
An iridoid glycoside has a variety of biological activities, including neuroprotective, anti-diabetic, anti-proliferative, and antioxidant activities. Gardenin has been shown to regulate Nrf2 translocation and up-regulate the expression of downstream antioxidant protein HO-1 via the PI3K/Akt signaling pathway. Glucagon-like peptide-1 (GLP-1) receptor may also play a key role in gardeniin-induced HO-1 expression.
Pharmacological action of Geniposide.
Geniposide has inhibitory effect on hemolytic streptococcus and skin fungi. It has antipyretic, analgesic, sedative, antihypertensive and hemostatic effects. Purging fire and eliminating boredom, clearing heat and dampness, cooling blood and detoxifying, eliminating swelling and pain. Symptoms include fever upset, manic disturbance, high fever irritability, dizziness and delirium, jaundice, red urine, heat and astringent pain, blood and heat epistaxis, eye red swelling pain, fire and poison sore; External treatment of contusion pain.
Product method of Geniposide.
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