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The combination of methylhesperidin and VitC can prevent hypertension and cerebral hemorrhage. Orange vitamin C granules have been developed in recent years. As early as the 1960s, it has become the main raw material of "maitong", and has become a vascular strengthening drug with other drugs, and is widely used in clinical practice.
Methylhesperidin is a flavonoid compound formed from hesperidin by methyltoxicity. It can increase coronary artery flow in isolated rabbits, increase cardiac output in dogs, reduce myocardial oxygen consumption, relax aorta in isolated rabbits, reduce vascular resistance in dogs' lower limbs, significantly reduce blood pressure, coronary artery, kidney and cerebrovascular resistance, and increase coronary and renal blood flow.
Uses and functions of Methyl hesperidin.
Methylhesperidin is a mixture of water-soluble dihydroflavonoid methylhesperidin. It has the same efficacy as vitamin P, can enhance the role of vitamin C, and has strong antiviral and antibacterial effects, large dose can inhibit the reproduction of influenza virus; It can inhibit the action of tyrosinase that causes skin blackening, and can be used to treat skin diseases such as dark spots and freckles. It can maintain the normal permeability of blood vessels, improve the resistance of capillary vessels, enhance the elasticity and toughness of capillary vessels, prevent and treat capillary bleeding, gingival bleeding, etc. It has the same pharmacological effect as hesperidin, can strengthen capillary resistance, make capillary infiltration normal and prevent vascular disorders caused by arteriosclerosis; It is more effective when used with vitamin C. It can be used for nosebleed, retinal hemorrhage, gum and alveolar hemorrhage. Gastrointestinal bleeding, hemorrhoidal bleeding, and bleeding prevention and treatment before or after surgery.
Synthesis method of Methyl hesperidin.
Methylhesperidin is derived from hesperidin (hesperidin R) methylation. The traditional process is to dissolve hesperidin in sodium hydroxide solution (sodium hydroxide method), and then add methylation reagent - dimethyl sulfate for methylation reaction to obtain methylhesperidin. The yield of this method is only 70.0%.
Product method of Bulk Methyl hesperidin Powder.
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