HRK Supply Pyridoxamine Dihydrochloride raw Materials powder

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Pyridoxamine Dihydrochloride Powder Usage and Synthesis.

Pyidomide hydrochloride is white or nearly white crystalline powder with a density of 1.282g/cm3, melting point 24-226°C(dec.)(lit.), boiling point 460.1º CAT760 MMHG, flash point 232.1ºC. Compound three-dimensional B for injection is a compound preparation, the components of which include furanothiamine hydrochloride, pyridoamine hydrochloride and vitamin B12, used for the treatment of peripheral nerve injury, polyneuritis, trigeminal neuralgia, pernicious anemia, nutritional anemia, etc.

Uses of Pyridoxamine Dihydrochloride.

1. Treat vitamin B6 deficiency

Improve anemia symptoms by promoting amino acid metabolism and heme synthesis.

2. Treat neuritis

It can enhance the function of the central nervous system and relieve the symptoms of numbness and tingling caused by peripheral neuritis.

3. Treatment of isoniazid poisoning

This product can counteract the neurotoxicity caused by isoniazid.

4. Treat hyperemesis gravidarum

It has anti-vomiting effect and can reduce the symptoms of nausea and vomiting during pregnancy.

5. Treat pellagra

Supplement the lack of vitamin B3 in the body to achieve the purpose of treating pellagra.

Dosage control should be paid attention to when using pyridoxine hydrochloride to avoid adverse reactions caused by excessive use. At the same time, this product is prohibited for allergic people, and should be used with caution for allergic people. Hematologic parameters should also be monitored regularly during medication, especially in patients who are prone to bleeding or are receiving anticoagulant therapy.

Pharmacological action of Pyridoxamine Dihydrochloride.

1. Metabolic regulation effect
As the active form of vitamin B6, it combines with ATP in the body to generate pyridoxamine phosphate, and participates in the decarboxylation, transamination and racemization reactions of amino acids (such as tryptophan and glutamate)
Promotes the conversion of linoleic acid to arachidonic acid, affecting lipid metabolism and arterial health

2. Nervous system support
Catalyzes the decarboxylation of glutamate to generate γ-aminobutyric acid (GABA), regulates central nervous system inhibitory transmitters, improves insomnia and nerve excitability
Relieves peripheral neuritis caused by drugs (such as isoniazid)

3. Blood and immune regulation
Participates in heme synthesis, improves sideroblastic anemia and leukopenia

4. Detoxification and anti-adverse reactions
Relieves vomiting caused by anticancer drugs, radiotherapy or pregnancy

Product method of Bulk Pyridoxamine Dihydrochloride Powder.

Pyridoxine hydrochloride was oxidized by manganese dioxide, condensed with hydroxylamine, and then reduced by zinc metal.

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