Nebivolol HCL Raw Materials Powder

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Nebivolol HCL Powder Raw Materials, Nebivolol HCL Raw Powder Manufacturer, Nebivolol HCl API Manufacturers,High Quality Nebivolol HCL Raw Materials used in the treatment of patients with mild to moderate hypertension, as well as in the treatment of angina pectoris and congestive heart failure. 

Uses and functions of Nebivolol HCL Raw Powder.

Nebivolol HCL is a potent, selective third-generation beta-blocker that blocks beta1 receptors 290 times more strongly than beta2 receptors, compared with 26 times more strongly than bisoprolol, 15 times more strongly than atenolol, and 1.9 times more strongly than propranolol.

Nebivolol HCL Powder is therefore more selective, does not cause contraction of bronchial smooth muscle and vascular smooth muscle, and has no endogenous sympathomimetic activity.

Pharmacological Effects of Purity Nebivolol HCL Powder.

Effects on cardiac function and haemodynamics: Nebivolol has no significant negative inotropic effect, on the contrary, it has a certain protective effect on cardiac function, which can reduce the cardiac preload, while the cardiac afterload is unchanged or slightly decreased.

The application of nebivolol increased ejection fraction in patients with heart failure, while pulmonary artery pressure and pulmonary capillary pressure did not change significantly.

Production method of Nebivolol HCL Powder.

Vasodilator effect: Nebivolol HCL Powder has an additional vasodilator effect, which is a significant advantage that distinguishes it from other beta-blockers.

Both the levodomain and the dextro-domain of nebivolol have vasodilatory effects, but the vasodilatory effect of the levodomain is endothelium-dependent, i.e., it exerts its vasodilatory effect mainly by enhancing the action of nitric oxide.

Nebivolol HCL Powder has no adrenergic α-receptor blocking effect and remains vasodilatory when the α-agonist benfotiamine is used.

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