Pharmaceutical raw material Bulk Methyl Hesperidin Powder

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Methyl Hesperidin Powder Usage and Synthesis.

Methyl Hesperidin and VitC can be used in combination to prevent hypertension, cerebral blood, and in recent years the development of orange Vitamin C punch; as early as the sixties to become the main raw material of "pulse", and other drugs with the strengthening of blood vessels to become a drug, widely used in clinical practice.

Uses and functions of Methyl Hesperidin.

It can be used to prevent and control hypertension, arteriosclerosis, cerebral haemorrhage, retinal haemorrhage, gum bleeding and so on. In addition, this product can inhibit the role of tyrosinase, which leads to skin discolouration, so it can be made into medicinal cosmetics, nutritional cosmetics and drugs for the treatment of black spots, freckles and other skin diseases.

It has the same efficacy as vitamin P, which can enhance the effect of vitamin C. It also has strong antiviral and antibacterial effects, and can inhibit the reproduction of influenza virus in large doses; it can inhibit the effect of tyrosinase that leads to the darkening of the skin, and it can be used to treat skin diseases such as dark spots, freckles, and so on. It has the ability to maintain the normal permeability of blood vessels, improve capillary resistance, enhance the elasticity and toughness of capillaries, preventing and treating capillary haemorrhage, bleeding gums and so on. It has the same pharmacological effect with hesperidin, can strengthen capillary resistance, make capillary permeability normal and prevent vascular disorders caused by atherosclerosis; better efficacy when used with vitamin C. It can be used for nosebleed, retinal bleeding, and other skin diseases. It can be used for nosebleed, retinal haemorrhage, gingival haemorrhage, alveolar haemorrhage. Gastrointestinal bleeding, haemorrhoidal bleeding, etc., as well as bleeding prevention and treatment before or after surgery.

Physiological Function of Methyl Hesperidin.

Methyl Hesperidin is a flavonoid compound formed by methyltoxicity of hesperidin, which can increase the flow of coronary artery in isolated rabbits, increase the cardiac output of dogs, reduce myocardial oxygen consumption, relax the aortic strips of isolated rabbits, reduce the vascular resistance of dogs' lower limbs, significantly reduce blood pressure and coronary, renal and cerebral vascular resistance, and increase the coronary artery and renal blood flow.

Synthesis method of  Bulk Methyl Hesperidin Powder.

Methyl Hesperidin is derived from the methylation of Hesperidin (Hesperidin R), the traditional process is by the liquid alkali method (sodium hydroxide method), the Hesperidin is dissolved in sodium hydroxide solution, and then add the methylation reagent - dimethyl sulphate for the methylation reaction to obtain methyl Hesperidin, the yield of this method is only 70.0%.

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