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Magnesium Gluconate (chemical formula: MgC12H22O14) is the magnesium salt of gluconic acid. It is white or off-white odourless fine powder. Soluble in water.
It is obtained by dissolving magnesium oxide or magnesium carbonate in gluconic acid. Used as nutritional supplement, buffer, curing agent and so on.
Note of Magnesium Gluconate.
1, this drug should be used under the supervision of a doctor, avoiding the combination with central nervous system depressants.
2、If diarrhoea occurs after taking this product, the dose should be reduced or discontinued as appropriate.
3, each time before the use of drugs should check the breathing and knee tendon reflex, if the respiratory <16 times / min, knee tendon reflex disappears, should stop using this product.
4、Pregnant women and lactating women: use under the guidance of a doctor.
Pharmacological Effectof Magnesium Gluconate.
Magnesium gluconate is dissociated into magnesium ion and gluconic acid in the body, which participates in all energy metabolism in the body and activates or catalyses more than 300 enzyme systems, and magnesium ions are involved in the synthesis of DNA and RNA, as well as in the structure of cell membranes.
This product has obvious muscle relaxation effect, can relieve coronary artery spasm, reduce the release of acetylcholine, maintain the balance of potassium and magnesium ions in the body, can prevent platelet aggregation and coronary thrombosis due to magnesium deficiency, has the effect of calcium conjugation resistance and membrane stabilisation.
Synthetics Method of Bulk Magnesium Gluconate Powder.
An aqueous gluconic acid solution of 1000 mL containing 25% gluconic acid was heated to boiling, and solid magnesium carbonate powder was added in batches under constant stirring until the pH of the solution remained close to 7, and then stirred for a few moments to make the reaction complete.
Then add appropriate amount of activated carbon decolourisation. Filtering while hot, the filtrate is slightly cooled and added to an equal volume of 95% ethanol, immediately a large number of white magnesium gluconate solid precipitation, filtration and vacuum drying below 100 ° C to obtain the product with two crystalline water.
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