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Folic acid is a water-soluble B vitamin that is involved in the synthesis of many important substances in the body, such as proteins, DNA and hemoglobin.
When there is a deficiency of folic acid in the body, it can result in the failure of red blood cells to mature, resulting in megaloblastic anemia. Folic acid has a wide range of medical applications, including its use in the treatment of megaloblastic anemia caused by various reasons and the prevention of neural tube malformations.
The recommended daily intake of folic acid varies according to age and is recommended by health authorities in different countries. Dihydrofolate, a derivative of folic acid, also has important medical applications.
Uses of Folic acid.
Folic acid can improve megaloblastic anemia, pregnant women intake of safe amount of folic acid can prevent vascular sclerosis, to prevent fetal malformation, preterm delivery; In addition, pregnant women need to be in the first trimester of pregnancy on the start of folic acid supplementation in order to meet the needs of the gestation period, because the general folic acid intake of the human body 4 weeks after the transformation can play a physiological role.
Lactating women can promote milk secretion by supplementing folic acid. Folic acid supplementation can improve tongue redness and pain, depression, fatigue, insomnia; prevent intestinal parasites and food poisoning; promote skin health, reproduce oral mucosal ulcers; with pantothenic acid and p-aminobenzoic acid together to prevent gray hair; when the body is weak to take can promote appetite.
Pharmacological effect of Folic acid.
Product Method of Bulk Folic acid Powder.
Cyclization reaction of p-aminobenzoylglutamic acid, 2,4,5-triamino-6-hydroxypyrimidine and trichloroacetone, in the presence of sodium metabisulfite and sodium acetate, keeping PH3.4-3.6 and temperature 36-40°C for 6h, yielded orange-red folic acid precipitate. Can also be used α,β-dibromopropionaldehyde instead of trichloroacetone, condensed under similar conditions to obtain the product.
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