Vitamin K1 Raw material powder Vitamin K1

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1, used to stop bleeding

Vitamin K1 is stored in the body is small, 3 to 4 weeks can be completely consumed in the body, so it needs to be often obtained from the gastrointestinal food, such as the acquisition of absorption process disorders, the synthesis of clotting factors related to the liver is inhibited, prothrombin is prolonged, leading to coagulation disorders, and cause bleeding symptoms, The main manifestations are skin and mucous membrane hemorrhage, visceral hemorrhage, post-traumatic hemorrhage, neonatal hemorrhage and other deep tissue hemorrhage.

2. Relieve spasm and pain

When the cause stimulates smooth muscle spasm and causes intense pain, vitamin K1 can be used together, the mechanism of action is: vitamin K1 has a selective can directly relax smooth muscle, while the smooth muscle contraction caused by acetylcholine has a significant inhibitory effect. Its analgesic mechanism is mediated by opioid receptors and endogenous opioids.

3. Treatment of bronchiolitis

Bronchiolitis is mainly caused by respiratory syncytial virus infection, mainly manifested as protrusion wheezing, there are obvious bronchiolar obstruction phenomenon, is a common pediatric emergency. In recent years, it has been found that bronchiolitis contains airway response mediated by immune cells to a large extent. A large number of inflammatory substances, such as viral IgE histamine-like substances and arachidonic acid, are found in tracheal secretions and blood of children with bronchiolitis, which are similar to those of asthmatic patients.

4, treatment of pediatric pneumonia

Vitamin K1 can adjust the contractile function of the microvascular system by antagonizing microvascular spasm, so as to improve hemorheology and adjust the microcirculation system, relieve the microcirculation disturbance caused by severe pneumonia in children, reduce the cardiac pre-and post-load, correct heart failure, reduce airway resistance, increase alveolar ventilation, and correct expiratory failure.

Uses of Vitamin K1.

Vitamin K dissolves in the lipid of mitochondrial membrane, plays an electron transfer role, vitamin K can increase intestinal peristalsis and secretion function, the lack of vitamin K smooth muscle tension and contraction is weakened, it can also affect the metabolism of some hormones. Such as delaying the decomposition of glucocorticoids in the liver, while having a similar effect to hydrocortisone, long-term injection of vitamin K can increase the endocrine activity of the thyroid.

Pharmacological action of Vitamin K1.

Product Method of Bulk Vitamin K1 Powder.

In the presence of zinc, acetyl menadione is produced by reduction and acetylation of o-methylnaphthoquinone and acetic anhydride. Then it was hydrolyzed in ammonia water, and then condensed with plant alcohol in ether under the catalysis of boron trifluoride to obtain dihydride vitamin K1. Finally, the product is obtained by hydrolysis, oxidation, purification and refining.

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