Cosmetic grade anti aging raw material L-Carnosine Powder CAS 305-84-0

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Carnosine Powder Usage and Synthesis

China Carnosine Raw Material Factory Supply Organic Carnosine Raw Material, High Quality Carnosine Powder Purity 99% Carnosine Powder, L-Carnosine Powder is a naturally occurring histidine-containing compound, and the biological role of this dipeptide is to act as a cytosolic buffer.

Manufactory Supply Carnosine Raw Material, High Purity Carnosine Powder, High Quality L-Carnosine Powder.

Uses and functions of L-Carnosine Powder

L-Carnosine is a dipeptide (two amino acids) often found in organs and tissues such as the brain, heart, skin, muscles, kidneys and stomach.

L-Creatinine activates cells in the body and fights aging through two mechanisms: inhibition of glycation and protection of our cells from free radicals, which cause uncontrolled cross-linking of sugar molecules and proteins (sugar molecules sticking to proteins), loss of cellular function and incomplete gene assembly, which accelerates aging.

L-Carnosine also stabilises cell membranes and reduces lipid peroxidation in the brain, thus preventing nerve and brain degeneration.

Pharmacological Effects of Carnosine Raw Material

L-Creatinine is a naturally occurring histidine-containing compound, and the biological role of this dipeptide is to act as a cytosolic buffer.

Other roles of L-creatinine include action as a neurotransmitter, regulation of enzyme activity, and chelation of heavy metals.

Levomyosin has potential antioxidant and anti-glycosylation activity; blocking acetaldehyde-induced non-enzymatic glycosylation and protein coupling.

It is also a substrate for the myrosinase assay, which maintains body pH balance and prolongs cellular life. UsesLeucomyosin is a dipeptide with strong antioxidant and anti-glycation activity;

Blocks non-enzymatic glycosylation and protein cross-linking induced by reactive aldehydes.

Production method of Carnosine Powder

• A) Preparation of hydrazinolysis reaction solution, in a 1000 ml four-necked reaction flask, put in 50 g (0.14 mol) of phthaloyl-L-creatinine peptide as an intermediate, 200 ml of water, hydrazine hydrate (mass percentage concentration of 80%) 10.8 g (0.17 mol), heated to reflux reaction for 1.0h. Add acetic acid to adjust the pH of the material to 5.5, filter to remove by-products, to get hydrazine solution;
• B) the preparation of L-myosin, to the hydrazide reaction solution obtained from step A) add 100ml methylene chloride and benzaldehyde 9.6g (0.09mol), stirring at room temperature for 12h, the material is static stratification, separated from the methylene chloride layer, the aqueous layer washed twice with 50ml methylene chloride and added 3g of activated carbon and 25ml of ammonia (18%), 60 ℃, decolourisation 0.5h, filtration and removal of by-products. Decolourisation was carried out for 0.5h, filtration was carried out to remove the activated carbon, the decolourised solution was concentrated in vacuum until a solid was precipitated, 300ml of methanol was added to crystallise the product, stirred for 2.0h and filtered, and the filter cake was dried at 100°C for 6h to obtain 28.6g of L-creatinine, no hydrazine residue was detected in the product.

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