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Magnesium diglycine is a compound that chelates magnesium ions with two glycine molecules. This unique structure makes it one of the most bioavailable forms of magnesium supplement on the market. Glycine, as an amino acid, not only promotes magnesium transport across the intestinal wall but also possesses its own calming properties, enhancing the relaxing effect of magnesium.
Compared to other forms such as magnesium oxide or magnesium citrate, magnesium diglycine has a neutral pH, making it gentler on the digestive system and significantly reducing the risk of side effects such as diarrhea—a common problem encountered by many when taking traditional magnesium supplements.
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How Magnesium Bisglycinate Works
I. Ultra-Efficient Intestinal Absorption
1. "Express-Track" Absorption:
Glycine is the simplest amino acid, and our intestines have specialized pathways for amino acid absorption.
When magnesium binds to glycine, it becomes like a "VIP pass," masquerading as an amino acid and utilizing these efficient, specialized pathways for absorption.
Result: This absorption method is water-independent, with a bioavailability of 70-90%, far exceeding that of magnesium oxide (approximately 4%) and even magnesium citrate.
2. Extremely Gentle on the Intestine:
Due to its extremely high absorption efficiency, virtually no excess magnesium molecules remain in the intestine to attract water.
Result: It rarely causes diarrhea or intestinal discomfort, a significant advantage over other magnesium salts (such as magnesium citrate and magnesium oxide).
II. Mechanism of Action
The Core Role of Magnesium Ions: The System's "Brake and Regulator"
1. The "Key" of GABA Receptors:
GABA is the primary inhibitory neurotransmitter in the brain, responsible for quieting the nervous system and acting as a "brake."
Magnesium binds directly to GABA receptors, enhancing GABA's calming effects and helping the brain transition from an excited state to a resting state.
2. "Gatekeeper" of NMDA Receptors:
Glutamate is the brain's primary excitatory neurotransmitter, acting like the "accelerator."
Magnesium sits on NMDA receptors (glutamate's primary site of action), preventing glutamate from overactivating neurons, thereby protecting nerves from the effects of excessive excitation and alleviating anxiety and nervous tension.
3. "Relaxant" for Muscles and Heart:
Magnesium regulates the flow of calcium ions into muscle cells, helping muscle fibers relax smoothly after contraction, relieving muscle tension, spasms, and cramps.
It also helps stabilize the heart's electrical activity and maintain a normal heart rate.
Glycine's Synergistic Effects: A "Specialized Tranquilizer" for the Nerves
1. "Brake Signal" in the Spinal Cord and Brainstem:
In the spinal cord and brainstem, glycine is the primary inhibitory neurotransmitter, directly signaling "stop" to motor neurons and tension signals, bringing a deep sense of relaxation to the body.
2. Improved Sleep Structure:
Studies have shown that glycine supplementation can lower the body's core temperature, a key step in initiating natural sleep.
It can help regulate sleep cycles, shorten the time it takes to fall asleep, deepen sleep, and help you feel more refreshed upon waking.
3. Anti-anxiety Support:
Glycine acts on glycine receptors in the brain, producing calming effects that can help relieve anxiety.
Target Group of magnesium bisglycinate capsules.
1. People with magnesium deficiency: People who do not get enough magnesium in their diet or need additional magnesium supplements.
2. People with high stress or sleep problems: People who want to relieve stress, anxiety or improve sleep quality.
3. Sports enthusiasts: People who need to relieve muscle spasms, cramps or speed up exercise recovery.
4. People who care about cardiovascular health: People who want to regulate blood pressure and support heart function.
5. People who need bone health: Elderly people or people at high risk of osteoporosis.
6. Women with premenstrual syndrome (PMS) who want to relieve premenstrual discomfort.
Doses of magnesium bisglycinate capsules.
Dosage: Usually 1-2 capsules per day, each capsule contains 100-200 mg of magnesium. For specific dosage, refer to the product instructions.
Time of use: Take with meals to improve absorption.
Continuous use: Long-term use is recommended for best results
Customer Case Studies:
Case 1:
"I tried five different magnesium supplements, all aiming to improve sleep, but each one caused stomach cramps. My functional medicine doctor recommended magnesium bisglycinate. These capsules have completely changed my life—not only do I sleep more deeply, but I also experience zero stomach discomfort. I'm finally getting the full benefits of magnesium."
Case 2:
"As a financial analyst, my brain can't stop working at night, and I also suffer from restless legs syndrome. After starting Magnesium Bisglycinate Capsules, not only has my mental tension significantly decreased, but most surprisingly, my leg discomfort has completely disappeared."
FAQ
Q: What is the difference between magnesium bisglycinate and other forms of magnesium?
A: The key differences lie in absorption mechanism and targeting:
Magnesium oxide/magnesium citrate: Breaks down in stomach acid, and the magnesium ions directly irritate the intestines, which can easily lead to diarrhea.
Magnesium bisglycinate: Absorbed intact through amino acid pathways, bypassing intestinal irritation and acting directly on the nervous system.
Q: What is the optimal time and dosage for administration?
A: For maximum relaxation and sleep benefits, we recommend taking two capsules 30-60 minutes before bedtime. For daytime stress support, take in divided doses with meals. Please follow the product label for specific instructions.
Q: Will this product cause dependency or drowsiness the next day?
A: No. Magnesium bisglycinate supports your body's natural circadian rhythms by replenishing essential minerals and is non-addictive. Its "relaxing, not sedating" properties help you wake up refreshed the next day.
Q: Is it necessary to take it with other nutrients?
A: Taking it with vitamin B6, taurine, or vitamin D3 can enhance its effects, but it is not necessary. Magnesium bisglycinate is a complete solution on its own.
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