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Product details
Fexofenadine, Fexofenadine hydrochloride, is an Antihistamine for systemic use. For seasonal allergic rhinitis, chronic idiopathic urticaria. The main ingredient of this product is fexofenadine hydrochloride. It is the main drug for treating allergic diseases such as allergic rhinitis, allergic skin disease and allergic asthma. Fexofenadine Powder is the internal metabolite of terfenadine. Fexofenadine Raw Materials is a third generation antihistamine. Fexofenadine Powder is a histamine H1 receptor antagonist. It is used to treat allergic rhinitis. It is contraindicated and has certain cardiotoxic side effects, but non-solifenadine has not been found to have cardiotoxicity. In just two years after its launch, its usage in the US market has risen to become the second largest variety and has maintained a strong growth momentum.
Pharmacokinetics of Fexofenadine Powder:
Fexofenadine is an antihistamine with selective peripheral H1 receptor antagonism. Fexofenadine inhibits histamine release from peritoneal mast cells in rats. In experimental animals, no anticholinergic, α1-adrenergic or β-adrenoceptor blocking effects were observed, nor were sedative or other central nervous system effects observed. Initial studies have found that terfenadine not only has pharmacological effects, but also its metabolites have pharmacological activity. If it is used directly to treat allergic reactions, it can avoid drug enzyme metabolism and eliminate cardiotoxicity to humans. Clinical studies have shown that fexofenadine Ding has a strong bronchial antispasmodic effect.
Clinical Application of Fexofenadine Powder:
1. Seasonal allergic rhinitis: It is suitable for the relief of symptoms related to seasonal allergic rhinitis in adults and children aged 6 and over. Such as sneezing, runny nose, itchy nose, palate, throat, itchy, moist, red eyes.
2. Chronic idiopathic urticaria: It is suitable for treating the skin symptoms of chronic idiopathic urticaria in adults and children aged 6 and over, and can reduce itching and the number of wheals.
Fexofenadine Powder Raw Materials can be made into drugs with the following properties:
(1) Fexofenadine hydrochloride capsules: the contents are white to off-white granules or granular powder.
(2) Fexofenadine Hydrochloride Tablets: film-coated tablets, which appear white or off-white after the coating is removed.
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