Pharmaceutical Chlorpromazine HCl Powder Raw Materials CAS 69-09-0 API Factory Supply

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Chlorpromazine HCl is a representative drug of phenothiazines. To the central nervous system, small doses have a stabilising effect, and large doses used continuously have an antipsychotic effect.

Chlorpromazine HCl inhibits the hypothalamic thermoregulatory centre, so that the body temperature rises and falls with the ambient temperature, and with other medicines, the body temperature falls below the normal temperature and the metabolism is lowered, which is called artificial hibernation.

Chlorpromazine HCl is mainly used for antipsychotics, to strengthen the hypnotics, anaesthetics, analgesics and anticonvulsants. It is also used as an antiemetic for vomiting and intractable eructation and to induce artificial hibernation.

Uses and functions of Chlorpromazine HCl Powder.

• 1. Treatment of psychosis: It is used to control the symptoms of schizophrenia or other psychotic disorders such as excitability, nervousness, hallucinations, delusions, etc. It is less effective in treating melancholic symptoms and symptoms of rigidity.
• 2. Antiemetic: It is effective in almost all causes of vomiting, such as uremia, gastroenteritis, cancer, pregnancy and drug-induced vomiting. It can also be used to treat persistent eructation, but it is ineffective in motion sickness vomiting.
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• 3. Hypothermia anaesthesia and artificial hibernation: it can prevent shock when used in hypothermia anaesthesia.
• 4. Combined with analgesics to treat severe pain in patients with advanced cancer.
• 5. Treatment of heart failure.
• 6. Trial in the treatment of gigantism.

Pharmacological Effects of Chlorpromazine HCl Powder.

From 2-chlorophenothiazine [92-39-7] condensation, salt formation.

1. condensation in the reaction pot to add 2-chlorophenothiazine and toluene, then add sodium hydroxide, stirring and heating reflux, remove water, at 110 ℃ dropwise addition of 1-chloro-3-dimethylaminopropane toluene soluble Chemicalbook liquid, the reaction will be decompression recovery of toluene, that is, to obtain chloropromazine, C17H19CIN2S , [50-53-3].2. Salt formation Chlorpromazine and isopropanol were heated to 40°C with stirring, and dry hydrogen chloride was passed through to pH 4-5, i.e., chlorpromazine hydrochloride was formed into a salt to obtain chlorpromazine hydrochloride.

Production method of Chlorpromazine HCl Powder.

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