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1.D3 Source: Synthesized by sunlight exposure to the skin (90% of the body's needs); foods such as deep-sea fish (salmon, sardines), egg yolks.Лучшие таблетки с витамином D3 и K2 для здоровья костей и суставов
2. K2 sources: fermented foods (natto, cheese), animal liver, grass-fed meats.Beste Vitamin D3 + K2 Tabletten für Knochen- & Gelenkgesundheit
3.Precautions:
Avoid overdose: D3 has a daily limit of 4000 IU, there is no clear upper limit for K2, but high doses may interfere with anticoagulant medications.Mejores tabletas de vitamina D3 + K2 para huesos y articulaciones
Special populations (e.g. pregnant women, people with abnormal liver or kidney function) need to be supplemented under doctor's supervision.Melhores comprimidos de vitamina D3 + K2 para ossos e articulações
Role and Function of Vitamin D3
1. Promote Calcium Absorption
D3 improves the efficiency of calcium absorption by activating calcium-binding proteins in the intestine. If D3 is deficient, even if sufficient amount of calcium is consumed, insufficient absorption may lead to osteoporosis or rickets.Meilleurs comprimés de vitamine D3 + K2 pour la santé osseuse & articulaire
2. Regulation of immunity and cell growth
D3 is involved in immune cell differentiation, inhibits inflammatory responses, and may reduce the risk of autoimmune diseases. In addition, it has a potential preventive effect on some cancers, such as colorectal cancer.
3. Bone Health Maintenance
D3, together with parathyroid hormone, regulates blood calcium levels to ensure normal bone mineralization and prevent osteochondrosis or increased risk of bone fracture.
Role and Function of Vitamin K2
1. Precise Regulation of Calcium Distribution
K2 activates two proteins: osteocalcin (which anchors calcium to bone) and matrix GLA protein (which inhibits vascular calcification). This mechanism reduces the risk of atherosclerosis.
2. Cardiovascular protection
K2 reduces the risk of coronary heart disease and stroke by inhibiting vascular calcification. Studies have shown that long-term K2 supplementation may be associated with decreased cardiovascular mortality.
3. Synergistic bone health
K2 enhances osteoblast activity and improves bone density, especially for postmenopausal women or the elderly with osteoporosis.
Synergy between D3 and K2
1. Optimization of Calcium Metabolism
D3 promotes calcium absorption while K2 ensures that calcium is properly utilized. Supplementing D3 alone may lead to elevated blood calcium, and in the absence of K2, excess calcium may be deposited in blood vessels or kidneys.
2. Reduces the risk of side effects
D3 overdose may trigger hypercalcemia, while K2 reduces such risk by activating related proteins. The combination of the two is safer and more efficient.
Deficiency Symptoms and Applicable People
D3 deficiency: bone pain, muscle weakness, decreased immunity, commonly seen in people with little sun exposure, dark skin or the elderly.
K2 deficiency: vascular calcification, osteoporosis, tooth enamel fragility, easy to see in long-term use of antibiotics or unbalanced diet.
Co-supplementation recommendations: people at high risk of osteoporosis, people with cardiovascular disease, chronic kidney disease or diabetes mellitus (subject to medical advice).
Natural Sources and Precautions
1.D3 Source: Synthesized by sunlight exposure to the skin (90% of the body's needs); foods such as deep-sea fish (salmon, sardines), egg yolks.
2. K2 sources: fermented foods (natto, cheese), animal liver, grass-fed meats.
3.Precautions:
Avoid overdose: D3 has a daily limit of 4000 IU, there is no clear upper limit for K2, but high doses may interfere with anticoagulant medications.
Special populations (e.g. pregnant women, people with abnormal liver or kidney function) need to be supplemented under doctor's supervision.
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Product formula and packaging can be flexibly customized according to your requirements, or according to our formula.
We provide multi-dosage service, like softgel, capsules,tablet, effervescent,gummy, drops and drink etc.
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Product Safety and Compliance Details
As the Food and Drug Administration (FDA) advises, dietary supplements can support your overall health but may also have powerful effects on the body. It’s important to read labels carefully, exercise caution, and consult your healthcare professional before taking any supplement. Side effects are more likely if supplements are taken in high doses, as substitutes for prescribed medications, or in combination with multiple supplements. If you experience severe side effects, discontinue use immediately and seek medical attention.
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