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Meloxicam Powder is a non-steroidal antipyretic and anti-inflammatory drug, not a hormonal drug, with strong anti-inflammatory, analgesic and Meloxicam Raw Materials is mainly used for the treatment of chronic diseases.
Meloxicam Raw Materials is mainly used to relieve the symptoms of osteoarthritis, painful osteoarthritis, rheumatoid arthritis and joint stiffness Like other NSAIDs.
Meloxicam CAS 71125-38-7 is mainly used for mild to moderate chronic dull pain, such as neuralgia and arthralgia. Cyclooxygenase-2 inhibitor for the treatment of symptoms of rheumatoid arthritis. Cyclooxygenase-2 inhibitor for the treatment of symptoms of rheumatoid arthritis, painful osteoarthritis.
Meloxicam is a non-steroidal antipyretic and anti-inflammatory drug, not a hormonal drug, with strong anti-inflammatory, analgesic and antipyretic effects, can selectively inhibit the activity of cyclooxygenase-2 (COX-2), thus blocking the synthesis of prostaglandins, the inhibition of prostaglandin biosynthesis at the site of inflammation is stronger than the prostaglandin biosynthesis in the gastric mucosa or kidney, and is safer than other NSAIDs. .
It is mainly used to relieve the symptoms of osteoarthritis, painful osteoarthritis, rheumatoid arthritis and arthritic spondylitis.
Application/Function of Meloxicam Powder.
1. Analgesic effect
Like other NSAIDs, meloxicam is mainly used for mild to moderate chronic dull pain, such as neuralgia and arthralgia. It has a strong and long-lasting analgesic effect on inflammatory pain in experimental rats. In male Lewis rats suffering from experimental RA, its dose of 0.063-0.5mg-kg-1, administered orally once a day for 21d, was not only effective on the redness and swelling of the hind paws and bone and cartilage damage, but also had strong and long-lasting analgesic effects on inflammatory pain, and the oral dose of up to 10mg-kg-1 had no effect on the central nervous system, similar to indomethacin. Meloxicam has no analgesic effect on visceral pain.
2. Antipyretic effect
Meloxicam can reduce the body temperature of febrile patients, but has almost no effect on normal body temperature. For example, in the anti-inflammatory dose range, meloxicam has no effect on normal body temperature in rats, but can reduce yeast-induced fever. For example, in the range of anti-inflammatory doses, meloxicam had no effect on normal body temperature in rats, but could reduce yeast-induced fever.
3. Anti-inflammatory effect
Meloxicam showed strong anti-inflammatory activity in animal inflammation models (mainly including rat hind paw edema model induced by gum carrageenan and white clay, rat granuloma model with cotton ball implantation, pleurisy induced by gum carrageenan and arthritis induced by Mycobacterium tuberculosis with liquid paraffin as adjuvant). Unlike indomethacin, meloxicam reduced pleuritic secretion and inhibited leukocyte migration in keratocystin-induced pleuritis.
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