Fosfomycin Sodium / Disodium Phosphonomycin Powder CAS 26016-99-9 Raw Materials

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Fosfomycin Sodium Powder Usage and Synthesis.

Fosfomycin Sodium Powder is a white crystalline powder at room temperature, Disodium Phosphonomycin Powder is hygroscopic, very soluble in water, exothermic when dissolved. Disodium Phosphonomycin Powder is hygroscopic, very soluble in water, exothermic when dissolved.

Fosfomycin Sodium Raw Materials is mainly used for the treatment of acute and chronic intestinal diseases caused by Staphylococcus aureus, Streptococcus, Escherichia coli, Staphylococcus, Streptococcus, and Staphylococcus. Streptococcus, Escherichia coli, Salmonella and other gram-negative bacteria in chickens, ducks, swine. 

Fosfomycin Sodium Powder is used to treat infections caused by Staphylococcus, Streptococcus, Escherichia coli, Salmonella and other gram-negative bacteria in chickens, ducks and swine. bacteria in chickens, ducks and swine.

Fosfomycin Sodium Powder is used to treat infections caused by Staphylococcus aureus, Escherichia coli, Proteus vulgaris, and dysentery.

Uses and functions of Fosfomycin Sodium Powder.

Fosfomycin sodium binds to a bacterial cell wall synthetase, blocking the first step of bacterial cell wall synthesis using the substance in question, thus acting as a bactericide.

It has antibacterial effect on Staphylococcus, Streptococcus pneumoniae, Escherichia coli, Gonococcus, Proteus mirabilis, Typhoid fever, Serratia marcescens, most of Pseudomonas aeruginosa, Streptococcus pyogenes, Streptococcus faecalis, some indole-positive Streptococcus pyogenes and some Klebsiella spp. and Enterobacteriaceae.

Fosfomycin sodium is mainly used clinically for the treatment of urinary tract, urinary system, skin and soft tissue, respiratory tract, intestinal tract and other parts of the infection caused by sensitive gram-negative bacteria.

It can also be used in combination with other antibiotics for the treatment of severe infections caused by sensitive bacteria such as sepsis, lung, meningeal infections, peritonitis, uterine adnexitis, intrauterine infections, pelvic inflammatory disease, osteomyelitis and so on.

It can also be combined with vancomycin to treat methicillin-resistant Staphylococcus aureus (MRSA) infections.

It is mainly used for the treatment of acute and chronic intestinal diseases caused by staphylococcus, streptococcus, E. coli, salmonella and other gram-negative bacteria in chickens, ducks and pigs.

For the treatment of infections caused by Staphylococcus aureus, Escherichia coli, Proteus mirabilis and dysentery bacilli.

Pharmacological Effects of Fosfomycin Sodium Powder.

• 1.Wide antimicrobial spectrum, high bioavailability, fast absorption, strong antimicrobial power, not affected by diet. It has killing effect on Gram-positive and negative bacteria, especially on Pseudomonas aeruginosa, Aspergillus, Salmonella, and Staphylococcus and Escherichia coli which are resistant to all kinds of drugs can show excellent antibacterial activity. Used in animals, there is no drug resistance and cross-resistance, good clinical therapeutic effect.
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• 2. Rapid bactericidal: this product is a rapid bactericidal agent, its effect is already obvious after 1-2 hours. About 25% of Escherichia coli are killed 1 hour after contacting Phosphomycin (12.5μg/ml), while all of them die within 4-6 hours. Pseudomonas aeruginosa and Staphylococcus aureus were also killed completely in 4 and 8 hours respectively.
• 3. Low toxicity and side effects, low stimulation to the organism, no acute toxicity and adverse reactions, will not aggravate the burden on the kidneys.
• 4. Low residual: the elimination time to reach the residual standard in muscle and organs is 48-72 hours.

Production method of Fosfomycin Sodium Powder.

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