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Lomefloxacin Hydrochloride is the hydrochloride form of Lomefloxacin.Lomefloxacin Hydrochloride Powder is a bactericidal fluoroquinolone with activity against Gram negative and Gram positive bacteria.
Lomefloxacin Hydrochloride Raw Materials is a familiar common anti-inflammatory drug, belonging to the quinolone class of synthetic antibiotics, this product has a wide antibacterial spectrum, long duration of action, strong antibacterial effect, good clinical efficacy and other characteristics.
Uses and functions of Lomefloxacin Hydrochloride Powder.
Lomefloxacin hydrochloride is a common anti-inflammatory drug that we are all familiar with, belonging to the quinolone class of synthetic antibiotics, which was firstly developed and was firstly researched and developed successfully in China by the China University of Pharmaceutical Sciences.
The inhibitory effect on resistant Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli is one to two times that of of ofloxacin and two to four times that of norfloxacin.
In vitro studies show that the antibacterial effect of lomefloxacin hydrochloride on gram-positive bacteria is stronger than enrofloxacin and similar to norfloxacin; the antibacterial effect on gram-negative bacteria is weaker than that of norfloxacin, ofloxacin, and similar to that of enrofloxacin; however, in vivo anti-infective effects are stronger than those of the above drugs.
Pharmacological Effects of Lomefloxacin Hydrochloride Powder.
Lomefloxacin hydrochloride is the hydrochloride form of Lomefloxacin. Lomefloxacin is a bactericidal fluoroquinolone that is active against Gram-negative and Gram-positive bacteria. Lomefloxacin inhibits bacterial DNA-promoting enzymes (topoisomerase II) and topoisomerase IV, which are required for bacterial DNA transcription and replication.
DNA-promoter enzymes are considered to be the primary quinolone targets in gram-negative bacteria. Topoisomerase IV is considered the primary target of Gram-positive bacteria. Inhibition of topoisomerases results in strand breaks, superhelixes, and resealing of bacterial chromosomes.
As a result, DNA replication and transcription are inhibited.
Lomefloxacin can be used to treat a wide range of infections including respiratory, urinary tract, obstetrical, gynecological, joint, skin, oral, ear, nose, throat and eye infections. Compared with other quinolone antibacterial drugs, lomefloxacin has the advantages of easy administration and no need for theophylline dose adjustment.
Production method of Lomefloxacin Hydrochloride Powder.
Lomefloxacin hydrochloride is a fluoroquinolone-containing antimicrobial agent. Lomefloxacin is a kind of DNA catalase antagonist.
It is mainly used for the treatment of acute and chronic infectious diseases caused by various gram-positive and negative bacteria.
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