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Bovine mushroom is a valuable fungus, and its extracts have attracted much attention in recent years. Studies have shown that Bovine mushroom extracts possess a variety of biological activities, including anticancer, antioxidant, anti-inflammatory, and immunomodulatory.
For example, Cinnamomum cassia extract can induce apoptosis in hepatocellular carcinoma cells while having no toxic effects on normal hepatocytes. In addition, Bovine mushroom extracts have potential anti-angioproliferative, hepatoprotective abilities.
Uses and functions of Antrodia Camphorata Extract.
Boswellia serrata extract has a variety of efficacies and effects. Firstly, it has a direct cytotoxic effect on a variety of cancer cells, such as liver cancer, breast cancer, leukaemia and pancreatic cancer.
Secondly, the polysaccharides, phenols, triterpenoids, and adenosine components in Cinnamomum oxyphyllum have certain neuroprotective effects, which can improve neurodegeneration and memory dysfunction.
In addition, the aqueous extract of Cinnamomum cassia has a lipid-regulating effect. Most importantly, the fruiting bodies of Ganoderma lucidum are very effective in lowering blood sugar and can be used in the treatment of diabetes.
Pharmacological Effect of Antrodia Camphorata Extract.
1.Anti-tumour effect
Studies have shown that the solids of Camphoria sinensis have anticancer effects, and the methanolic extract of Camphoria mycelium, Camphoria acid A, had a significant inhibitory effect on lymphoid tumour cells of P-388 mice.
The mycelia of M. camphorata showed significant cytotoxicity against HL-60 cells with leukocytosis, but not against human endothelial cells cultured artificially.
Tumour inhibition experiments on the filtrate of liquid culture of S. camphorata strain CCRC930032 showed that the culture medium filtrate of this strain could strongly inhibit the growth of mammary tumour cells (MCF-7), cervical tumour cells (Hela), gastric tumour cells (AGS), intestinal tumour cells (COLO205, COLO320HSR), hepatic tumour cells (Hep3B2.1-7), colon tumour cells (CaCoCo), and other tumour cells (Hep3B2.1-7). Tumour cells (CaCo-2) and erythrocyte tumour cells (ES-2) and other cell lines.
2.. Anti-inflammatory effects
The triterpenoid camphoric acid isolated from the fruiting bodies of Ganoderma lucidum possesses anti-inflammatory activity, and the aqueous extract of mycelium from deep culture of Ganoderma lucidum also possesses similar anti-inflammatory activity.
The size of anti-inflammatory effect is in the following order: the fruiting body of C. camphorata > solid fermented C. camphorata > liquid fermented C. camphorata.
3.Other effects
The water and methanol extracts of the fruiting bodies of Camphoria japonica have inhibitory effect on the growth of Staphylococcus aureus and Serratia marcescens, and the polysaccharide of Camphoria japonica has antiparasitic property.
The methanolic extract of Camphoria japonica has platelet coagulation effect, while Camphoria japonica B has weak anticholinergic and anti-5-hydroxytryptophan effects, and Camphoria japonica also has skin rejuvenation function.
The extract of C. camphorata effectively inhibited the apoptosis of neuron-like pheochromocytoma (PC12) cell line, indicating its protective effect on neuronal cells.
Chemical Components of Bulk Antrodia Camphorata Extract Powder.
The 3,11-dioxo-8,23-dien-26-oic acid was obtained from the seeds of C. camphorata by extraction with acetone, and camphoric acid A and camphoric acid B were obtained from the methanolic extract of C. camphorata, and the solids of C. camphorata obtained by solid cultivation had similar constituents such as polysaccharides and triterpenoids as the wild form.
Two phenyl compounds were isolated from the fruiting bodies of C. camphorata, and their structures were determined by spectroscopy and 2DNMR as methyl 2,5-dimethoxy-3,4-methylenedioxybenzoate and 4,5-dimethoxy-2,3-methylenedioxybenzoate.
The polysaccharides were extracted from the fruiting bodies, mycelium and filtrate obtained from the solid and liquid cultures of Ganoderma lucidum, and the monosaccharides in the polysaccharides mainly consisted of mannose, glucose, xylose, galactose, galactosamine, glucuronic acid, and ribose, and the content of the soluble sugars, such as arabinose, glucose, and alginate, was more than 10%, and the contents of proteins were 9.49%-29.1%, and the contents of total amino acids were 7.01%-11.1mg-g-g-1. 11.1mg-g-1dry weight, Camphoria also contains monosodium glutamate-like substances, bitter substances and spices 5-nucleosides, Camphoria mycelium has a sweet taste.
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