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According to research, jujube polysaccharide can enhance muscle strength, increase body weight, enhance endurance, resist fatigue, and promote bone marrow hematopoiesis, enhance immunity, improve energy metabolism in rats with qi and blood double-deficiency model, promote calcium absorption, effectively reduce the time of intestinal peristalsis, improve the intestinal environment, and reduce the intestinal mucosa's exposure to toxic substances and other harmful substances.
Uses and functions of Jujube Polysaccharide.
Jujube polysaccharide is an important active substance in jujube, which has various effects and functions.
Firstly, jujube polysaccharide can significantly improve the immune function of immunosuppressed mice, promote the operation of qi and blood, elevate the level of cytokines promoting hematopoiesis and excitation of immunity-related cytokines in serum, and improve the tissue morphology, ultrastructure and energy metabolism level of the thymus and spleen tissues.
Secondly, jujube polysaccharide can also enhance muscle strength, increase body weight, enhance endurance, anti-fatigue, promote bone marrow hematopoiesis, enhance immunity, improve energy metabolism in rats with qi and blood double-deficiency model, promote calcium absorption, effectively reduce the time of intestinal peristalsis, improve the intestinal environment, and reduce the intestinal mucosa's exposure to toxic substances and other harmful substances.
In addition, jujube polysaccharide can also protect the liver, enhance physical strength, reduce the damage of chemical drugs on the liver, and has the effect of promoting protein synthesis and increasing the content of total serum protein, which can be used in the adjuvant treatment of chronic hepatitis and early cirrhosis.
Pharmacological effect of Jujube Polysaccharide.
1. Hematopoietic function: jujube polysaccharide is the main active ingredient of jujube to replenish qi and generate blood, and it was used to treat the mouse model of qi and blood double deficiency, and it was found that jujube polysaccharide had a very good improvement effect on the model of qi and blood double deficiency, and jujube polysaccharide showed the effect of promoting bone marrow hematopoiesis and stimulating immunity to the mouse model of qi and blood double deficiency through elevating the serum granulocyte-macrophage colony-stimulating factor (GM-CSF) of the model of qi and blood double deficiency. In addition, some studies have found that
In addition, it was found that jujube polysaccharide has obvious improvement effect on whole blood cells of rat qi and blood double deficiency model, and it can make erythrocyte membrane Na+-K+-ATPase, Mg2+-ATPase, Ca2+-ATPase and Ca2+-Mg2+-ATPase activity significantly higher than that of model group, which indicates that jujube polysaccharide can also improve energy metabolism of rat qi and blood double deficiency model.
2. Antioxidant effect: Jujube polysaccharide has an antioxidant effect on various reactive oxygen species in the human body, which is due to the fact that polysaccharide molecules have reducing hemiacetal hydroxyl groups, which can undergo redox reactions with oxidizing agents - reactive oxygen species.
In whole blood chemiluminescence, jujube polysaccharide has the strongest scavenging ability for reactive oxygen species, followed by the scavenging ability for -OH. The scavenging effect of jujube polysaccharide sample solution on O2-- and -OH was even higher than that of Vc. In addition, the scavenging effect of polysaccharides on NO2-- in vitro was determined under different pH conditions, and the results showed that the scavenging effect of polysaccharide solution on NO2-- was higher than that under the neutral pH conditions under the conditions of pH 2-6, which indicated that the polysaccharides had a higher antioxidant capacity under acidic conditions.
Add jujube polysaccharide to the drinking water of rats, and measure the content of free radicals in their serum, the results show that jujube polysaccharide has a certain effect on the serum free radicals of rats.
3. Repair liver injury, anti-fatigue effect: It was found that jujube polysaccharide can make the alanine aminotransferase (ALT) activity and aspartate aminotransferase (AST) activity level in mice significantly reduced, and can improve the histopathological changes of liver caused by CCl4; in addition, jujube polysaccharide can significantly improve the reserve of myo-glycogen and hepatic glycogen as well as the post-exercise lactic acid dehydrogenase (LDH) activity, but the effect on the post-exercise blood urea nitrogen was not significant. However, it had no effect on the blood urea nitrogen (BUN) value after exercise.
This suggests that jujube polysaccharide has a protective effect on CCl4-induced acute liver injury in mice, and also has an obvious anti-fatigue effect.
Preparation method of Bulk Jujube Polysaccharide Powder.
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