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Flutamide powder Usage and Synthesis.1. Anti-androgen
Flutamide has an anti-androgen effect by blocking androgen receptors and reducing testosterone levels in the body.
2. Inhibit estrogen synthesis
The drug can interfere with multiple links in the cholesterol metabolism process, reduce the liver's ability to synthesize estrogen, and indirectly play a role in inhibiting estrogen.
3. Improve prostate cancer symptoms
Flutamide can reduce the stimulation of androgens on prostate cells and reduce the symptoms of frequent urination and urgent urination caused by prostate cancer.
4. Alleviate prostate cancer progression
The drug has an anti-tumor effect that can slow the growth of prostate cancer cells and prevent further deterioration of the disease.
5. Improve your quality of life
After the use of flutamide, the patient's condition is controlled or alleviated, the related discomfort can be reduced or eliminated, and the quality of life and mobility can be improved.
Uses of Flutamide powder.
Non-steroidal androgen antagonists inhibit the conversion of testosterone into dihydrotestosterone and can block the binding of dihydrotestosterone to intracellular receptors in the prostate at the cellular level, thus inhibiting the growth stimulating effect of androgens on the prostate. It is effective orally. For the treatment of prostate cancer and prostatic megaly and luteinizing and releasing hormone - Lianpu, can treat advanced prostate cancer, prostatic megaly. Anticancer and antiandrogen drugs. It is used to treat advanced prostate cancer and prostatic hypertrophy that cannot be treated with surgery or radiation.
Pharmacological action of Flutamide powder.
Flutamide competes with androgens for androgen receptors at tumor sites, blocks uptake of androgens by cells, and inhibits the binding of androgens to target organs. After binding with androgen receptor, the product forms a receptor complex, enters the nucleus, and binds to nuclear protein, thus inhibiting the growth of tumor cells.
Product Method of Bulk Flutamide powder.
Trifluoromethyl benzene was nitrated to produce m-nitrotrifluoromethyl benzene, reduced to m-trifluoromethyl aniline, and reacted with isobutyryl chloride, and then nitrated to produce flutamide.
Or by the acylation of 3-trifluoromethyl - 4-nitroaniline and isobutyryl chloride.
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