Veterinary Medicine Nitenpyram Powder CAS 150824-47-8 Raw Materials

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Nitenpyram Powder Usage and Synthesis.

Nitenpyram Powder can also be used to control fleas and ticks on cats and dogs.Veterinary Medicine Nitenpyram has a broad spectrum of insecticidal activity. Nitenpyram Raw Materials is mainly used to control stinging insect pests such as aphids, rice fly, sooty fly, whitefly, pear louse, leafhoppers, etc.

Nitenpyram Raw Materials is a neonicotinoid insecticide with unique chemical and biological properties. Nitenpyram Raw Materials is a neonicotinoid insecticide with unique chemical and biological properties.Nitenpyram Powder acts mainly on insect nerves and has a nerve blocking effect on insect synaptic receptors.

Uses and functions of Nitenpyram Powder.

Nitenpyram can be widely used in agriculture and horticulture, such as rice, fruit trees, vegetables and tea, to prevent aphids, rice lice, whiteflies, leafhoppers, thrips and other piercing-sucking mouthparts, with ultra-high efficiency, wide insecticidal spectrum, unique mode of action, low dosage, low toxicity, long-lasting efficacy, no harmful effects on the crop, low toxicity to humans, and safe to use. Its advantage is that it has no interactive resistance with mainstream neonicotinoid insecticides imidacloprid and thiamethoxam.

• 1、Prevention and control of aphids: use 10% soluble liquid or 10% water 2000~3000 times liquid evenly spray. Can also be used as a soluble granule of 10% enediamine 2000 times liquid irrigation, the greenhouse cucumber aphid has a good prevention effect, 10 days after the drug population reduction rate are more than 96%. The period of efficacy can reach more than 20 days.
• 2, the prevention and control of whitefly, whitefly: with 10% enediamine soluble liquid 2000 uniform spray, but also in the planting of 10% enediamine water 2000 ~ 3000 times liquid. For the overlap of generations (adult, larvae, eggs) and the high population base of the field, the prevention effect is outstanding, and the holding period can be up to about 20 days.
• 3、Thrips prevention and control: Dilute 3000 times of 10% enediamine soluble liquid + 5% acetamiprid 2000 times of liquid and spray evenly. The control effect is outstanding.
• 4、Preventing and controlling ticks: during the period of outbreak of ticks, evenly spraying with 10% enediamine 2000 times liquid, the preventive effect reaches more than 90%, and the effect is significantly better than that of 30% acetamiprid. The quick-acting nature is very obvious, and the holding period can reach about 15 days.

Pharmacological Effects of Nitenpyram Powder.

Nitenpyram is a nicotinic acetylcholinesterase receptor inhibitor, which has the effect of endocytosis and osmosis. It mainly acts on insect nerves, inhibits the activity of ethylphthalide cholinesterase, and acts on cholinergic receptors, enlarging the septal potential difference after spontaneous discharge and decreasing the synaptic septal stimulation, resulting in loss of stimulation of the nerve's axonal septal potential channel, and has a nerve-blocking effect on the axonal synaptic receptor of the insect, resulting in the death of the insect by paralysis.

The insect will be paralysed and die. Due to the high water solubility and low partition coefficient of Nitenpyram, the toxicity of Nitenpyram to animals is low, and most of the metabolites can be excreted with the metabolism in the body.

Production method of Nitenpyram Powder.

2-Chloro-5-chloromethylpyridine is a pesticide intermediate for the synthesis of enidiamide, which is not only used for the synthesis of enidiamide, but also an important intermediate for other neonicotinoid insecticides such as imidacloprid, acetamiprid and thiamethoxam.

There are two main synthesis processes: both routes start with the synthesis of the key intermediate N-(6-chloro-3-pyridinylmethyl)-N-ethylamine (Intermediate 2).

• The first route involves the synthesis of intermediate 3 via 1,1-dimethylthio-2-nitroethylene.
• The second route is to make intermediate 4 by 1,1-dichloro-2-nitroethylene, and then finally to react with methylamine to obtain the final product, allylcarbamate.

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