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Pefloxacin mesylate is a broad-spectrum antibiotic that belongs to the fluoroquinolone class of antibiotics. It can inhibit bacterial DNA synthesis, thus killing or inhibiting the growth of bacteria. Pefloxacin Mesylate is mainly used to treat urinary tract infections, respiratory tract infections, skin and soft tissue infections, and gastrointestinal tract infections. When using Pefloxacin Mesylate, you should follow your doctor's prescription and follow the dosage and dosing cycle to avoid drug abuse and unnecessary side effects. Pefloxacin mesylate belongs to the fluoroquinolone class of antibacterial drugs.
It has the characteristics of broad antibacterial spectrum, strong activity, quick absorption and easy use. It has broad-spectrum activity against Gram-negative and Gram-positive bacteria, including enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter, Haemophilus, Neisseria and Staphylococcus (including methicillin-resistant strains). The resistance of staphylococcus aureus to vancomycin was similar to that of vancomycin, and some multi-drug resistant strains and methicillin-resistant bacteria were also effective. Pefloxacin was sensitive to Staphylococcus aureus resistant to penicillin G and benzoxicillin.
Pharmacokinetics of Pefloxacin Mesylate Powder:
Pefloxacin has a broad antimicrobial spectrum and strong antimicrobial activity, and its mode of action is inhibition of bacterial DNA cyclooxygenase. The efficacy of pefloxacin in certain severe infections is comparable to or exceeds that of third and fourth generation cephalosporins, new aminoglycoside antibiotics and ciprofloxacin. Pefloxacin currently plays an important role in the antimicrobial therapy of various septic infectious diseases, especially central nervous system infections, cardiovascular infections, respiratory infections, gynecological infections and bone infections.
Pefloxacin mesylate is a third generation quinolone drug, and its mechanism of action, like other quinolones, is to bind to bacterial DNA gyrase subunit A, thus inhibiting the cleavage and linkage function of the enzyme, preventing the replication of bacterial DNA and presenting antibacterial effects. Pefloxacin mesylate is suitable for the prevention and treatment of infectious diseases of the digestive tract and respiratory tract of livestock and poultry caused by various bacteria, and is effective in the prevention and treatment of avian coliform disease, chicken dysentery, avian typhoid fever, chicken oviductitis, duck epidemic pasteurellosis and piglets yellow and white dysentery, piglets paratyphoid fever, porcine streptococcal disease, cow mastitis and other diseases.
Clinical Application of Sarafloxacin Hydrochloride Powder:
1. Pefloxacin mesylate has a wide antibacterial spectrum and strong antibacterial effect.
2... Pefloxacin Mesylate is a bactericidal agent that inhibits bacterial DNA helicase. It can block DNA synthesis and produce rapid bactericidal effect.
3. Pefloxacin mesylate has good antibacterial activity against a variety of Gram-positive and negative bacteria, and has high sensitivity to -lactam and aminoglycoside resistant strains, and has synergistic effect with most antibiotics. This product is rapidly absorbed, and long half-life, a long-acting drugs.
4. Pefloxacin mesylate has excellent water solubility, it can dissolve more than 90g per 100ml of water, with rapid oral absorption, high blood concentration and long half-life of 10-12 hours. It is widely distributed in body tissues and fluids.
5. Pefloxacin mesylate has higher efficacy when used in combination with metronidazole.
Sarafloxacin hydrochloride is a fluoroquinolone antibiotic used to treat bacterial infections such as respiratory, urinary tract, and skin infections in animals. It works by inhibiting bacterial DNA gyrase, which is an essential enzyme for bacterial DNA replication and repair. Sarafloxacin hydrochloride is absorbed quickly and has a long half-life, which allows for once-daily dosing. However, it is not approved for use in humans due to its potential to cause serious side effects, such as joint cartilage damage and phototoxicity. Its use in Animals is also limited due to concerns about the development of antibiotic resistance.
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