Related Attributes
Product details
By inhibiting the conversion of tetrahydrofolate to folate, sulfachlorpyridazine sodium interferes with the biosynthesis of aminobenzoic acid (PABA) and thus inhibits bacterial replication. Only microorganisms that produce their own folic acid are sensitive to sulfonamides. The microorganisms sensitive to sulfonamides include some gram-positive bacteria, such as streptococcus, staphylococcus, Bacillus anthracis, Bacillus tetanus, Bacillus actinomyces and Bacillus perfringens. Gram-negative bacteria, such as E. coli, Salmonella, Proteus, Klebsiella, intestinal bacteria, etc.; Coccidioides such as actinobacillus, Rickettsiella and toxoplasma protozoa. However, in recent years, resistance to sulfonamides is emerging year by year. Sulfonamides are not effective against microorganisms in pus, necrotic tissue and local cell debris.
Uses of Sulfachloropyridazine sodium.
Blocking microbial tetrahydrofolate synthesis. It has a broad spectrum of antibacterial action and can resist gram-positive and Gram-negative bacteria. The blood concentration reached the highest value within 1-3 hours of internal administration. Sulfonamides. For livestock and poultry (pigs, chickens) E. coli and Pasteurella infection. Used as an anti-inflammatory and antibacterial drug for livestock, mainly used for chicken Escherichia coli, staphylococcus infection, white crown disease, chicken fever and other infectious diseases.
Pharmacological action of Sulfachloropyridazine sodium.
The antibacterial profile is similar to sulfamethoxine, but the antibacterial action is slightly weaker than sulfamethoxine. Blocking microbial tetrahydrofolate synthesis. It has a broad spectrum of antibacterial action and can resist gram-positive and Gram-negative bacteria. The blood concentration reached the highest value within 1-3 hours of internal administration. Sulfonamides. For livestock and poultry (pigs, chickens) E. coli and Pasteurella infection.
FAQ.
Q1: Can Sulfachloropyridazine Sodium be used in combination with other drugs?
A: Yes, but it should not be used in combination with procaine penicillin (as this may reduce efficacy). Combination with TMP (trimethoprim) can enhance antimicrobial efficacy.
Q2: What is the withdrawal period? When can slaughter or marketing occur?
A: Generally 5–7 days, depending on the animal species and regulatory requirements.
Q3: How should Sulfachloropyridazine Sodium be stored?
A: Store in a sealed, light-protected, dry place, avoiding high temperatures and humidity.
Sulfonamide drugs commonly used in veterinary medicine.
| Drug Name | Main Uses | Suitable Animals | Features |
| Sulfadiazine | Respiratory tract infections, sepsis | Pigs, poultry, cattle | Often used in combination with trimethoprim (TMP) to enhance efficacy |
| Sulfamethoxazole (SMZ) | Gastrointestinal and urinary tract infection | Dogs, cats, cattle | Compound formulations (e.g., SMZ+TMP) |
| Sulfachloropyridazine sodium | Avian cholera, swine streptococcal disease | Chickens, pigs | Highly water-soluble, suitable for group administration |
| Sulfaquinoxaline | Coccidiosis, avian cholera | Poultry | Also has anti-coccidial activity |
| Sulfamethazine (Sulfamethazine) | Mastitis, respiratory infections Dairy | cows, pigs | Short withdrawal period |
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