Hydroxy Methylbutyrate raw Powder beta-Hydroxyisovaleric Acid

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Hydroxy Methylbutyrate Physiological effects.

Creatine derivative of 3-hydroxy-3-methylbutyrate (HMB, also known as β-hydroxy-β-methylbutyrate) 3-hydroxy-3-methylbutyrate creatine (HMB creatine) is a metabolite of leucine. It can be used to promote animal muscle growth, enhance the immunity of mammals, lower the levels of cholesterol and low-density lipoprotein (LDL) in the human body to reduce the occurrence of coronary heart disease and cardiovascular disease, and can also help enhance the body's nitrogen fixation ability and maintain protein levels in the body. It is widely used.

Uses of Hydroxy Methylbutyrate.

Preparation of Hydroxy Methylbutyrate.

347 g (0.620 mol) of a 13.3 wt% sodium hypochlorite aqueous solution was added to the flask, cooled, and 20.0 g (0.172 mol) of diacetone alcohol was added while maintaining the temperature at 0°C-10°C. Stirring was continued at 0°C-10°C for 15 minutes to allow diacetone alcohol to react with sodium hypochlorite.

The reactant was then acidified with 60.8 g (0.600 mol) of hydrochloric acid (pH: 1.0), concentrated to a residual weight of 125 g (approximately 30% of the weight before concentration), and 3-hydroxy-3-methylbutyric acid (HMB) free acid was collected by extraction with ethyl acetate (45 mL × 3 times). The mixture of the three extracts was concentrated to obtain 14.9 g of HMB free acid (0.126 mol in terms of HMB)

Product Method of Hydroxy Methylbutyrate.

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