Avobenzone CAS 70356-09-1 Raw Materials Powder

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Avobenzone Powder Usage and Synthesis.

Avobenzone Powder is an organic compound with the chemical formula C12H9N, a kind of aromatic compound.Avobenzone CAS 70356-09-1 is a colorless crystal with strong aromatic odor.Avobenzone Raw Materials is an important industrial raw material, widely used in dyes, pharmaceuticals, pesticides and other fields. In addition, Avobenzone can also be used as an intermediate in organic synthesis, and is widely used in organic synthesis reactions. Avobenzone CAS 70356-09-1 is a benzophenone UV absorber, which is also an important intermediate in organic synthesis.

Application/Function of Avobenzone Powder.

Avobenzone (Avobezone) is A synthetic UV absorber. It is a good UV-A(> 320nm) UV absorber, which can block UVA in the full band (320 ~ 400nm). It is an efficient broad-spectrum oil-soluble UVA filter. Provides full UVA and UVB protection against photogenic skin cancer.

Avobenzone (Butyl methoxydibenzoylmethane, BF2AVB) is an oil-soluble sunscreen that absorbs the full spectrum of UVA rays and is a Dibenzoylmethane derivative.

Pharmacological effect of Avobenzone Powder

Avobenzone, Chinese name: butylmethoxybenzoylmethane, is one of the few organic sunscreens that can absorb UVA1, which is the largest span of UV rays and the wavelength region that most UV absorbers cannot protect against: 340-400 nm.

The significance of protection against UVA is considerable and may outweigh sun protection: UVA reaching the earth's surface accounts for 95% of total UVB, and only recently have scholars discovered that UVA is not only a major cause of photoaging of the skin, but is also involved in the process of sunlight-induced carcinogenesis. Compared to only 10% of UVB that can reach the uppermost dermis, 20-30% of UVA can reach the dermis.

Avobenzone is used primarily as a chemical sunscreen, which typically works by absorbing the sun's ultraviolet rays and releasing them as heat.

Synthesis method of Avobenzone Powder

At present, the main methods for synthesizing avobenzone are:

• 1.condensation addition elimination hydration method, that is, p-methoxyacetophenone and p-tert-butylbenzaldehyde after condensation, bromine addition, elimination into alkyne, hydration to get the product, yield of 58%, the method route is long, high cost, low yield;
• 2. Claisen ester condensation method, that is, the reaction of p-methoxyacetophenone with methyl p-tert-butylbenzoate, the yield is 63.6%, the method is low cost, easy to operate, but the yield is low;
• 3.Aldehyde and ketone condensation method, i.e. p-methoxyacetophenone and p-tert-butylbenzaldehyde were obtained by condensation to alcohol and oxidation with a yield of 34.6%, which is easy to operate, high cost and low yield.

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