Cabozantinib Malate CAS 1140909-48-3 Raw Materials Powder

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Cabozantinib Malate Powder Usage and Synthesis.

Cabozantinib Malate Powder is a small molecule C-Met modulator. Cabozantinib malate acts as a potent multi-target VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50s of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively.

Cabozantinib Malate CAS 1140909-48-3 showed dose-dependent inhibition of tumor growth and tumor regression associated with disruption of the tumor vascular system and extensive tumor apoptosis.

Cabozantinib Malate Raw Materials primarily targets MET and VEGFR2 tyrosine kinases associated with prostate cancer growth and proliferation, inhibiting tumor metastasis and vascular The main target of Cabozantinib Malate Raw Materials is MET and VEGFR2 tyrosine kinases, which are associated with prostate cancer growth and proliferation, to inhibit tumor metastasis and angiogenesis.

Application/Function of Cabozantinib Malate Powder.

Cabozantinib Malate was developed by Exelixis Biopharmaceuticals, Inc. It targets MET and VEGFR2 tyrosine kinases, which are associated with the growth and spread of prostate cancer, to inhibit tumor metastasis and angiogenesis.

Pharmacological effect of Cabozantinib Malate Powder

CabozantinibS-MALATE, formerly known as XL184, was developed by Exelixis Biopharmaceuticals, Inc. It targets MET and VEGFR2 tyrosine kinases, which are associated with the growth and spread of prostate cancer, to inhibit tumor metastasis and angiogenesis.

Cabozantinib malate, the malate salt of Cabozantinib, is a potent VEGFR2 inhibitor with an IC50 of 0.035nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2 and AXL with IC50s of 1.3nM, 4nM, 4.6nM, 12nM/11.3nM/6nM, respectively. 14.3nM and 7nM.

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