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Neohesperidin dihydrochalcone can be added to food, medicine and feed as a taste modifier to mask bitter taste. Neohesperidin dihydrochalcone also has the function of modifying the flavor of the product itself, including modifying the taste and flavor of the product. NHDC has an excellent effect of improving taste, this product can be used in the food industry, pharmaceutical industry and feed industry as a sweetener (or taste correction agent), in the flavor has excellent use.
The addition of this kind of compound sweetener products to animal rations can greatly improve the flavor and palatability of feed, the aroma of NHDC and vanilla in the sweetener, cover up and improve the adverse bitter taste of some ingredients in the diet (such as some protein raw materials, vitamins, metal ions and some pharmaceutical ingredients, etc.), thereby increasing the appetite of young animals and promoting their growth.
New hesperidin dihydrochalone is a very important flavonoid compound, which is obtained from raw materials extracted from rutaceae plants through conversion and hydrogenation. It belongs to green food additives. Compared with other sweeteners, it has high sweetness, long aftertaste duration, good stability, low calories, and no adverse effects on human blood lipid and blood sugar levels.
Uses of neohesperidin dihydrochalcone.
Neohesperidin dihydrochalcone is a dihydrochalcone flavonoid compound prepared by hydrogenation of neohesperidin. In 1963, Horowits et al. discovered for the first time that neohesperidin dihydrochalcone has a strong sweetness. It is characterized by high sweetness, low heat, slow sweetness, long time, good stability and non-toxicity. In 1997, it was included in China's "health standard for the use of food additives", and the emergence of new hesperidin dihydrochalcone brought good news to the use of sugar for diabetic people and middle-aged and elderly people. At present, it is widely used in food, feed and pharmaceutical industries.
Neohesperidin dihydrochalone has strong antioxidant activity, can also reduce blood sugar and lipids, inhibit fatty liver, regulate immunity and other important physiological activities. Choi et al. showed that neohesperidin dihydrochalone can significantly remove stable free radicals and reactive oxygen species (ROS), and can effectively inhibit and remove hydrogen peroxide and hypochlorous acid. Moreover, neohesperidin dihydrochalone also inhibited protein degradation and DNA strand breakage, which indicated that neohesperidin dihydrochalone could be used in the treatment of diseases caused by reactive oxygen species
Preparation of neohesperidin dihydrochalcone.
NHDC as a new type of natural high-power sweetener, high sweetness, no calories, and high safety, known as "almost perfect" sweetener, its application scope is gradually expanding. The application of instantaneous extraction technology at room temperature and high pressure can save the amount of extraction solvent by 50%, reduce the extraction time by 80%, reduce the energy consumption by 30% and increase the yield by more than 20%.
The application of membrane concentration technology solves the problem of high concentration energy consumption in production, reduces energy consumption by more than 50%, and retains its heat-sensitive active ingredients. The problem of low solubility of NHDC in cold water was solved by adding 10~20 glucose groups to the branch chain by enzyme technology, which greatly expanded the application range of NHDC.
Product Methods of Bulk neohesperidin dihydrochalcone powder.
The new hesperidin was extracted from the peel of Citrusaurantium (Sevilleorange) with water, and then naringin and hesperidin were removed according to their solubility in water. It is then dissolved in KOH solution, hydrogenated under pressure in the presence of palladium-carbon catalyst, and then filtered, acidified, crystallized and recrystallized at low temperature.
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