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Rosmarinic Acid Usage and Function.

Rosmarinic acid has strong anti-inflammatory activity, while rosmarinic acid also has antibacterial, antiviral, anti-tumor activity, and has the ability to inhibit acute and chronic infection, anti-ultraviolet, inhibit elastin degradation and other properties have made rosmarinic acid become a cosmetic additive. At present, rosmarinic acid has shown its important application value in pharmaceutical, food, cosmetics and other fields.

In summary, rosmarinic acid has a very broad application prospect and market value, the main application areas:

1. Food field: Rosmarinic acid, as a natural and highly effective antioxidant, can replace BHA and BHT in animal and vegetable oils, dairy products, oil-rich foods, confectionery and baked goods; It can also be used as a spice in a variety of soups and flavored foods; It also has antiseptic and antibacterial effects. In Japan, Perilla extract, which is rich in rosmarinic acid, is used as a decoration to improve the shelf life of fresh seafood.

2. Health care products: anti-tumor, anti-hepatitis and liver damage protection, anti-nephritis, anti-thrombosis and anti-platelet aggregation, as well as refreshing, enhancing memory, improving tension and lethargy and other effects.

3. Cosmetics: Used in skin care products can play a role in removing color spots, antioxidant, increase skin elasticity, delay aging and so on; Used in shampoo products, it can promote scalp blood circulation, improve hair loss, reduce dandruff occurrence, stimulate hair growth, and moisten hair. Rosmarinic acid can be used as an excellent additive in cosmetics.

Uses of Rosmarinic Acid.

antioxidation

Rosmarinic acid has strong free radical scavenging activity and antioxidant effect in the body. The mechanism is as follows: rosmarinic acid and unsaturated fatty acid competitively bind to lipid peroxy group to terminate the chain reaction of lipid peroxidation and reduce the rate of lipid peroxidation, while rosmarinic acid is oxidized to quinone form; Smarinic acid can inhibit neutrophil respiratory burst and lysosome release by reducing intracellular calcium concentration. Inhibits endothelial cell-regulated low-density lipoprotein oxidation. The antioxidant effect of rosmarinic acid is related to its structure. Nakamura et al believe that o-diphenol hydroxyl group is the material basis for scavenging free radical activity. Moreover, the conjugated double bonds at C3 have a synergistic effect.

Antidepressant effect

Rosmarinic acid has antidepressant effect on animal model of depression. ItoN et al. conducted experiments on cell proliferation in the hippocampal gyrus of rats, conducted immunohistochemical analysis with bromodeoxyuridine antibodies, and explored its mechanism of action. They found that in the rosmarinic acid treatment group, the number of labeled proliferative cells increased, and combined with the forced swimming test of depressed animal models, it was indicated that rosmarinic acid at least partially promoted the proliferation of new cells in the hippocampal gyrus and produced an antidepressant-like effect.

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