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Artemether is a highly effective and rapid insecticide in the internal phase of Plasmodium erythrocyte. It is used for the treatment of chloroquine falciparum malaria and dangerous malaria, and has a rapid effect and good short-term effect.
Artemether not only has a strong killing effect on the internal asexual reproductive body of red blood cells, but also can promote the liver migration and killing of adult schistosomiasis, and it is also effective on the schistosomiasis children at different developmental stages. The children who are 1 week old are the most sensitive to the drug, and the effect on female worms is more obvious than that on male worms, and the immediate effect is good. It is mainly used for anti-chloroquine falciparum malaria treatment and emergency treatment of dangerous falciparum malaria.
Uses of Artemether.
Artemether has a direct killing effect on the internal red phase of Plasmodium, but has no effect on the tissue phase. The toxicity to experimental animals is very low. It absorbs mass in the body, distributes widely, and is excreted quickly. According to the electron microscope observation, the action site of this product on Plasmodium falciparum is mainly the membrane structure, and the mechanism of its antimalarial action is believed to interfere with the function of plasmodium membrane-mitochondria.
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