Natural Rosemary Extract Ursolic acid Raw Materials powder

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Ursolic acid powder Usage and Synthesis.

Ursolic acid has obvious antioxidant function and is a strong antioxidant. The antioxidant effect of ursolic acid plays a positive role in anti-aging, skin freckle removal and pigment removal of the human body, so it is widely used as a raw material for medicine and natural whitening cosmetics. Experiments have shown that ursolic acid can inhibit the activities of 5-lipoxygenase and cycloxygenase during the metabolism of arachidonic acid. Prostaglandins and leukotrienes are prevented, which may be the reason why ursolic acid inhibits inflammation and lipid peroxides.

Uses of Ursolic acid powder.

Ursolic acid is a triterpenoid compound found in natural plants, which has sedative, anti-inflammatory, antibacterial, anti-diabetic, anti-ulcer, lowering blood sugar and other biological effects. Ursolic acid also has obvious antioxidant function. In addition, ursolic acid can inhibit cell cycle process, cell proliferation and metastasis by inducing cell apoptosis. And demonstrate its anticancer activity by reducing tumorigenesis through multiple signaling pathways.

Current experimental studies have shown that ursolic acid inhibits a variety of cancers, including bladder, colon, breast, cervical, stomach, glioma, neuroblastoma, fibrosarcoma, liver cancer, leukemia, multiple myeloma, lung cancer, ovarian cancer, pancreatic cancer, thyroid cancer, melanoma, and prostate cancer. In order to further understand and study the role of ursolic acid on cancer and open up a new chapter of chemotherapy, scientists have carried out a variety of in vivo and in vitro studies.

Pharmacological action of Ursolic acid powder.

1. ‌Antitumor effect‌
Inhibits cell proliferation of various malignant tumors (such as glioblastoma, lung cancer, gastric cancer, liver cancer, etc.)

Exerts anticancer effect by blocking cell cycle, inducing apoptosis (regulating Bcl-2/Bax, activating Caspase pathway), and inhibiting epithelial-mesenchymal transition (downregulating FAK/PI3K/AKT pathway)

Can enhance sensitivity to radiotherapy and chemotherapy and inhibit tumor angiogenesis

2. ‌Antibacterial and anti-inflammatory effect‌
Has obvious antibacterial activity against bacteria

Anti-inflammatory effect is stronger than commercially available anti-inflammatory drugs such as indomethacin

3. ‌Other physiological activities‌
Lowers body temperature in rats and has a stabilizing effect

Similar to triterpenoids such as oleanolic acid and glycyrrhizic acid, it may have potential effects such as anti-diabetes and lipid regulation

Product method of Bulk Ursolic acid powder.

It is found in the whole grass of the labiaceae plant Prunella vulgaris L. and in the leaves of Ilex rotunda Thunb.

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