Supply Oxiracetam Raw Materials powder

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Oxiracetam of Usage and Synthesis.

Oxiracetam is a commonly used neurotropic drug in clinic, which is often used in the treatment of vascular dementia, senile dementia and memory and cognitive dysfunction caused by craniocerebral trauma. Clinical studies have shown that it can effectively enhance the memory of dementia patients, improve their cognitive ability, and effectively improve their living standards.

Oxiracetam can promote the transport of acetylcholine in the cerebral cortex, increase the affinity of brain cells for choline uptake, improve the activity of brain phosphatase A1, and inhibit the decomposition of brain lecithin, thus effectively activating acylate activating enzyme, improve the synthesis of adenosine triphosphate (ATP) in the brain, and increase the energy storage in the brain. Effective Yin can improve the insufficient energy metabolism caused by ischemia and hypoxia and promote the energy metabolism of brain cells.

Uses of Oxiracetam.

Oxiracetam, the analogue of piracetam, has a central excitatory effect, can promote brain metabolism, significantly improve and promote brain memory, and is effective for senile memory and mental decline. After taking this product, most of it is excreted in the urine of the prototype drug, which does not accumulate in the body, and is well absorbed and well tolerated. It can be used for brain dysfunction and memory loss in the elderly, especially for senile dementia, and can also be used for rehabilitation treatment of neurosis, brain trauma, encephalitis and other brain diseases.

Pharmacological action of Oxiracetam.

Oxiracetam is a ring-shaped derivative of r aminobutyric acid, which has been shown to have multiple protective and restorative effects on brain function. After entering the human body, oxiracetam can selectively act on the cerebral cortex for binding, and can selectively activate and protect brain tissue and promote the functional recovery of damaged nerve cells, so as to improve and integrate brain functions, such as memory, learning ability, cognitive ability, etc. Therefore, oxiracetam is often used as a combination drug for the treatment of various cerebrovascular diseases. Such as cerebral infarction, cerebral hemorrhage and so on.

Product method of Bulk Oxiracetam Powder.

4-amino-3-hydroxybutyric acid reacts with dimethylsilylamine to protect the hydroxyl group, then lactam is formed into lactam, and the amino group is alkylated with ethyl 2-bromoacetate to form 2-oxo-4-trimethylsiloxy-1-pyrrolidine ethyl ester, which is hydrolysed to remove the protective group on the hydroxyl group and then ammonolysis to oxiracetam.

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