API intermediates Diphenhydramine Hcl Raw Powder

CAS:147-24-0

MF:C17H22ClNO

MW:291.82

EINECS:205-687-2

Specification: 99% min Diphenhydramine Hcl Powder

Sample:Diphenhydramine Hcl Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Diphenhydramine Hcl Powder Usage and Synthesis.

Diphenhydramine hydrochloride, the name of a western medicine. Common dosage forms are tablets and injections. Oral tablets are used for allergies of the skin and mucous membranes, such as urticaria, allergic rhinitis, pruritus, drug rash, and are also effective for insect bites and contact dermatitis. It is also used for the prevention and treatment of motion sickness.

Injection for acute severe allergic reactions, can reduce blood transfusion or plasma-induced allergic reactions; post-surgery drug-induced nausea and vomiting; Parkinson's disease and extrapyramidal symptoms; dental local anaesthesia, when the patient is highly allergic to commonly used local anaesthetics, 1% diphenhydramine solution can be used as dental local anaesthetics; other allergic reactions to the disease, it is not suitable for oral use of drugs.

Uses and functions of Diphenhydramine Hcl.

Diphenhydramine hydrochloride is mainly used for: allergy of skin and mucous membranes, such as urticaria, angioneurotic oedema, allergic rhinitis, pruritis, drug rash, and is also effective for insect bites and contact dermatitis; prevention and treatment of motion sickness, with strong antiemetic effect; Parkinson's disease and extrapyramidal symptoms; sedative, hypnotic; strengthening the effect of cough suppressant, suitable for the treatment of cough due to cold or allergy.

(1) Antihistamine effect, can compete with histamine released from tissues for H1 receptors on effector cells, thus stopping allergic reactions;

(2) Sedative-hypnotic effect caused by inhibition of central nervous activity;

(3) Enhances the action of cough suppressants;

(4) It also has the effect of anti-vertigo and anti-tremor paralysis. Product Name Diphenhydramine Hydrochloride Appearance Properties White crystalline powder.

Pharmacological Effect of Diphenhydramine Hcl.

Diphenhydramine hydrochloride tablets:

This product is a derivative of ethanolamine, which competes with histamine released from tissues for H1 receptors on effector cells. This prevents the onset of allergic reactions and relieves the spasmogenic and congestive effects of histamine. In addition, this product also has a strong antiemetic effect.

Diphenhydramine Hydrochloride Injection:

Derivatives of ethanolamine, antihistamine effect is not as good as isoprinosine, the duration of action is also shorter, sedative effect of the two drugs is consistent with local anaesthesia, antiemetic and anti-M cholinergic-like effect.

1、Antihistamine effect, can compete with the histamine released from the tissues on the effector cell H1 receptor, so as to stop the allergic reaction.

2、Inhibition of central nervous activity causes sedative-hypnotic effect.

3、Strengthen the effect of cough suppressant.

4、Anti-vertigo, anti-tremor paralysis effects.

Drug interactions of Bulk Diphenhydramine Hcl Powder.

1、This product can transiently affect the absorption of barbiturates and sodium sulfacetamide acetylsodium.

2, and p-aminosalicylic acid sodium can reduce the latter blood concentration.

3、It can enhance the effect of central nervous system depressant drugs.