Natural 20(s)-protopanaxadiol Powder

CAS:30636-90-9

MF:C30H52O3

MW:460.73

EINECS:/

Specification​: 99% min 20(s)-protopanaxadiol Powder

Sample:20(s)-protopanaxadiol Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

20(s)-protopanaxadiol Powder Usage and Synthesis.

Protopanaxadiol belongs to the dammarane-type triterpenoids. It is a natural product found mainly in plants of the family Pentacostaceae, such as ginseng and American ginseng. Protopanaxadiol has a variety of biological activities, including antioxidant, anti-inflammatory and anti-tumour effects.

In addition, it has a variety of pharmacological effects such as regulating the immune system and protecting the cardiovascular system. Protopanaxadiol has a wide range of applications and can be used in pharmaceuticals, health products, cosmetics and other fields.

In terms of chemical structure, protoginseng diol has a six-membered ring and a five-membered ring, of which the six-membered ring is a dammarane ring and the five-membered ring is a cyclopentane ring. It has a complex stereo structure with multiple chiral centres. The chemical structure of proto-ginseng diol can be identified by various methods such as infrared spectroscopy and nuclear magnetic resonance.

Uses of 20(s)-protopanaxadiol.

Protopanaxadiol is a chemical with the molecular formula C30H52O3, which is mainly found in herbal medicines such as ginseng, ginseng and Panax ginseng. According to research, proto-ginseng diol has a variety of efficacy and effects.

Firstly, proto-ginseng diol has anti-tumour effects. In experiments, proto-ginseng diol can inhibit the growth and spread of tumour cells and promote their apoptosis.

Secondly, proto-ginseng diol also has antioxidant and anti-inflammatory effects. It can scavenge free radicals, reduce oxidative stress, and inhibit the production of inflammatory factors, thereby reducing inflammatory responses and tissue damage.

In addition, proto-ginseng diol can regulate the immune system and enhance the body's immunity. It can promote the proliferation and activation of immune cells and improve the body's resistance to pathogens.

Pharmacological Effect of 20(s)-protopanaxadiol.

Total ginsenosides and monomer compounds have important roles in promoting apoptosis of tumour cells, inducing differentiation of tumour cells, increasing sensitivity of tumour cells to chemotherapeutic drugs, inhibiting tumour neovascularization, improving body's anti-tumour immunity and inhibiting tumour growth and metastasis.

In vivo studies of Bulk 20(s)-protopanaxadiol Powder.

In the elevated cross maze test, treatment with PPD (20(S)-Protopanaxadiol) and PPT (20(S)-Protopanaxatriol) prior to restraint stress prolonged the open-arm retention time and the number of open arms.

Treatment with PPD effectively suppressed serum levels of corticosterone and IL-6 induced by restraint stress.PPD and PPT may exert their anxiolytic effects through GABAA receptors and serotonin receptors, respectively.The anti-inflammatory effect of PPD was stronger than that of PPT.