Etoposide CAS 33419-42-0 Raw Materials Powder

CAS: 33419-42-0

MF: C29H32O13

Specification​: 99% min Etoposide Powder

Sample: Etoposide Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https:https://henrikang.en.made-in-china.com/

Etoposide Powder Usage and Synthesis :

Etoposide (etoposide) is chemically known as 9-(4,6-O-ethylidene-β-D-glucopyranoside)-4′-demethylepipodophyllotoxin. It is also known as etoposide, pedipalposide, pedipalposide, pedipalposide, pedipalposide, etc. It is off-white crystalline powder, odorless. It is easy to change color when exposed to light and heat, and has moisture-attracting property. 

Almost insoluble in water, slightly soluble in methanol, dimethyl sulfoxide, slightly soluble in ethanol. Etoposide is a new semi-synthetic epigallocatechin derivative, which is a mitotic inhibitor, causing cells to stop at mid mitosis, and is a cell cycle specific anticancer drug.

Etoposide Powder is a common anti-cancer drug also known as topotinib.Etoposide Raw Materials is a tyrosine kinase inhibitor used to treat a variety of cancers, including lung, liver, colon, stomach and breast cancers.Etoposide CAS 33419-42-0 works by inhibiting growth and proliferation of tumor cells, thereby achieving a therapeutic effect on cancer.

Application/Function of Etoposide Powder :

Etoposide has a wide range of applications and has been widely used in clinical treatment. It can be used alone or in combination with other chemotherapeutic drugs to achieve better therapeutic effects. However, it is important to note when using etoposide that it is not used for all types of cancer and may interact with other drugs. Therefore, before using etoposide, you should consult your doctor's advice to ensure safe and effective use.

In conclusion, etoposide is an important anti-cancer drug that can be used to treat a variety of cancers. When using etoposide, one should pay attention to the dosage and usage, follow the doctor's advice, and monitor the occurrence of adverse reactions and side effects. By using etoposide correctly, it can help patients better control their cancer and improve their survival rate and quality of life.

The experimental study found that the complex can be reversed with the elimination of the drug. topo II free, so that the damaged DNA is repaired and its anti-tumor effect is reduced, so the prolonged dosing time can improve the anti-tumor activity. It is mainly used for the treatment of small cell lung cancer, malignant lymphoma, malignant germ cell tumor, leukemia, and is effective against neuroblastoma, rhabdomyosarcoma, ovarian cancer, non-small cell lung cancer, gastric cancer and esophageal cancer.

Production method of Etoposide Powder :

Etoposide is pharmacologically characterized by rapid absorption and metabolism in the body, with maximum concentrations occurring 2-4 hours after administration and a half-life of approximately 4 hours. It is mainly metabolized by the liver and, to a lesser extent, excreted by the kidneys. Therefore, monitoring of liver and kidney function needs to be observed when using etoposide.

The main side effects of etoposide include nausea, vomiting, diarrhea, rash, fatigue, headache, and dry mouth. When using etoposide, you should follow your doctor's advice and avoid overdosing and long-term use to reduce the occurrence of adverse reactions and side effects.

The dose and usage of etoposide should be adjusted according to the patient's specific situation and condition. In general, the initial dose of etoposide is 400 mg/day divided into two oral doses. If tolerated by the patient, the doctor may gradually increase the dose to a maximum of 800 mg/day.

It is mainly used for the treatment of small cell lung cancer, testicular tumors, malignant lymphoma, and acute leukemia. It is also effective in neuroblastoma, rhabdomyosarcoma, ovarian cancer, non-small cell lung cancer, gastric cancer, and breast cancer.

Drug Interactions.

• 1. Due to the obvious myelosuppressive effect of this product, care should be taken when combined with other antitumor drugs.
• 2. This product can inhibit the body's immune defense mechanism, so that vaccination can not stimulate human antibody production.
• 3. Viral vaccination is not recommended within 3 months after the completion of chemotherapy.
• 4. The product has a high binding rate with plasma proteins, therefore, the excretion of the product can be affected by drugs bound to plasma proteins.