Biletin / Nobiletin / Chuanpi Glycosides CAS 478-01-3 Powder

CAS: 478-01-3

MF: C21H22O8

MW: 402.39

Specification​: 99% min Biletin / Nobiletin / Chuanpi Glycosides

Sample: Biletin / Nobiletin / Chuanpi Glycosides Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Nobiletin Powder Usage and Synthesis.

Biletin CAS 478-01-3 (Hexamethoxyflavone) is an O-methylflavone, a flavonoid isolated from citrus fruit peels such as tangerine. Nobiletin Powder is a citrus flavonoid isolated from citrus fruit peels such as tangerine that has anti-inflammatory and anti-tumor activities. Nobiletin may also prevent atherosclerosis at the level of the blood vessel wall by inhibiting the formation of macrophage sponge cells.

Chuanpi Glycosides Powder has anti-clotting, anti-thrombotic, anti-cancer, anti-fungal, anti-inflammatory, anti-inflammatory, anti-viral. anti-cancer, anti-mutagenic, anti-allergic, anti-ulcer, analgesic, hypotensive activity, and blood cholesterol lowering Effects.

Application/Function of Nobiletin Powder.

Nobiletin has anti-blood cell coagulation, anti-thrombosis, anti-cancer, anti-fungal, anti-inflammatory, anti-allergic, anti-cholinesterase and anti-epileptic effects, and is a carbohydrate metabolism promoter. White to light yellow crystalline powder, belongs to flavonoids. Bittering agent.

The product is hydrogenated to obtain naringin dihydrochalcone as a sweetener, which is about 150 times sweeter than sucrose. Naringin has anti-inflammatory, anti-viral, anti-cancer, anti-mutagenic, anti-allergic, anti-ulcer, analgesic, hypotensive activity, can lower blood cholesterol, reduce the formation of blood clots, improve local microcirculation and nutrient supply, and can be used in the production of prevention and treatment of cardiovascular diseases.

The cold winter months can easily lead to the onset of coronary heart disease, and patients with coronary heart disease should pay attention to diet, keep warm, and take medication regularly, in addition to the appropriate amount of Chen Pi tea to protect the heart. The Chuan Chen Pi in Chen Pi tea can prevent heart disease, diabetes and stroke, and can also control weight. Studies have found that the chenopodin in chenopodium tea is 10 times more than that in grapefruit.

Chuan Chen Piin has anti-blood cell coagulation, anti-thrombosis, anti-fungal and anti-inflammatory effects, is a carbohydrate metabolism enhancer, improves local microcirculation and nutrient supply, and is suitable for use in the prevention of cardiovascular disease and its role in preventing heart disease.

Chen Pi infusion tea is one of the simple methods. According to Chinese medicine, Chen Pi is warm in nature, pungent and bitter in taste; it enters the spleen, stomach and lung meridians and has the effects of regulating qi and drying dampness, resolving phlegm and relieving cough, strengthening the spleen and stomach.

 Orange peel is dried and concocted into Chen Pi, the longer the peel is aged, the better it is, and should generally be left for another year before use, or you can buy it directly from a pharmacy. It should be reminded that, although Chen Pi is good, but Chen Pi infusion is not for everyone to drink, with fever, dry mouth, urine and other symptoms, should not use Chen Pi infusion to drink, should be under the guidance of a physician.

Details of the role of Sichuan chenpi elements:

• 1, cancer prevention and anti-cancer effects
• Chuan Chen Pi has the role of preventing the development of tumors, lung cancer, peritoneal tumors, gastric cancer, colon cancer, fibroids have * anti-cancer activity, and a variety of tumor cells have inhibited the proliferation effect. It is mainly related to its antioxidant effect, inhibition of cancer cell-related enzyme activity and induction of cell cycle arrest.
• 2、Cardiovascular system activity
• Flavonoids such as Chuan Chen Pi can regulate blood lipids, reduce blood viscosity, improve serum lipids, prolong the life span of red blood cells and enhance hematopoiesis, prevent cardiovascular diseases, and many effective Chinese patent medicines for coronary heart disease contain flavonoids.
• 3、Antibacterial and antiviral activity
• Chuan Chen Pi has a certain antibacterial effect, can enhance the body's non-specific immune function and humoral immune function, enhance resistance.
• 4、Anti-aging effect
• Chuan Chen Pi elements have * antioxidant scavenging effect of free radicals, the stronger the body's antioxidant ability, the healthier and longer life.
• 5 Anti-inflammatory and analgesic activity
• Chuan Chen Pi and other flavonoids have anti-inflammatory and analgesic effects, which can be used clinically to treat abscesses and ulcers as well as inflammatory diseases caused by pathogenic microorganisms.
• 6、Hepatoprotective activity

It can inhibit lipid peroxidation in liver tissues, increase liver SOD activity and reduce lipofuscin formation in liver tissues, which has a protective effect on the liver and can protect the damage of liver cell ultrastructure caused by ethanol.

In addition, a large number of studies have shown that Chuan Chen Piin and other flavonoids also have pharmacological activities such as hypotension, hypolipidemia, anti-aging, improving body immunity, laxative, cough suppressant, expectorant and antispasmodic.

Pharmacological effects of Chuan Chen Piin

Chuan Chen Piin has anti-blood cell coagulation, anti-thrombosis, anti-cancer, anti-fungal, anti-inflammatory, anti-allergic, anti-cholinesterase and anti-epileptic effects, and is a carbohydrate metabolism promoter.

Naringenin has anti-inflammatory, anti-viral, anti-cancer, anti-mutagenic, anti-allergic, anti-ulcer, analgesic, and hypotensive activities. It can lower blood cholesterol, reduce the formation of blood clots, improve local microcirculation and nutrient supply, and can be used to prevent and treat cardiovascular diseases.

Physical description

Melting point and solubility: the content of water of crystallization in pure naringin and its melting point vary depending on the crystallization and drying methods. The naringin molecule obtained by crystallization with water as solvent contains 6-8 water of crystallization and its melting point is 83℃; while the naringin molecule obtained after drying to constant weight at 110℃ contains 2 water of crystallization and its melting point rises to 171℃. It is soluble in methanol, ethanol, acetone, acetic acid, dilute alkali solution and hot water, and its solubility in water is 0.1% at room temperature and up to 10% at 75℃.