Astragalus Polysacharin CAS 89250-26-0 Raw Materials Powder

CAS: 89250-26-0

MF: C10H7ClN2O2S

Specification​: 99% min Astragalus Polysacharin Powder

Sample:  Astragalus Polysacharin Powder

Brand: Henrikang

Appearance: Brown Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Astragalus Polysacharin Powder Usage and Synthesis

Astragalus Polysacharin Powder is a polysaccharide compound extracted from Astragalus, Astragalus Polysacharin Raw Materials has a variety of biological activities and pharmacological effects.Astragalus Polysacharin CAS 89250-26-0 can Improve body immunity, antioxidant, anti-tumor and anti-inflammatory effects, and have protective effects on cardiovascular disease, liver disease and kidney disease. In addition, Astragalus polysaccharide can also regulate blood sugar, lower blood lipids, and promote intestinal health. Therefore, Astragalus polysaccharide is widely used in health care products, drugs, cosmetics and other fields.

Astragalus polysaccharide is an active ingredient of traditional Chinese medicine extracted from Astragalus mongolica or Astragalus membranaceus, containing Astragalus polysaccharide in glucose (C6H12O6), which should be not less than 65% for oral liquid grade and not less than 70% for injection grade.

Astragalus is a Chinese herbal medicine to benefit qi, and it has been confirmed that the astragalus polysaccharide, choline and many kinds of Vitamins contained in it can obviously improve the function of human leukocytes to induce interferon, regulate body immunity and contribute to antibody formation. By regulating and inducing interferon to destroy the virus in the body to achieve therapeutic effect.

Applications of Astragalus Polysacharin Powder :

Astragalus polysaccharide injection can be used for the treatment of variant viral colds, acute and chronic respiratory diseases and bacterial and mycoplasma infections caused by viral diseases in livestock and poultry; it also has auxiliary therapeutic effects on circovirus, blue ear disease, pericarditis, encephalitis, infectious gastroenteritis, epidemic diarrhea and epidemic mumps; in addition, it can prevent the spread and remedy the failure of immunization against pustules on the mouth, nose and feet and virulent infectious diseases.

1、Improve the immunity of the body, prevent and control the immune system syndrome of livestock and poultry, have the function of promoting the growth of animals, improve the appetite of chickens, enhance digestive power, improve disease resistance, improve survival rate, improve feed conversion rate by 9.0% and 10.1%, can significantly improve the egg production rate of laying hens, reduce the feed-to-egg ratio and mortality rate, and can improve the production performance of laying hens at the peak of egg production.

2、Astragalus polysaccharide can block the adhesion of Pseudomonas aeruginosa in the respiratory epithelium and has a repairing effect on the tracheal mucosa epithelium of mice with chronic bronchial lesions, which can play the role of anti-Pseudomonas aeruginosa infection.

3. Certain polysaccharides contained in traditional Chinese medicine are important immune agents, such as ginseng polysaccharide, shiitake mushroom polysaccharide, astragalus polysaccharide and antler polysaccharide. Astragalus polysaccharide has a comprehensive enhancement effect on cellular immunity, humoral immunity, molecular immunity, complement immunity, etc. It has a preventive effect for patients with frequent colds and flu, and has the efficacy of supporting the toxicity of chronic infections, but it can activate antibodies, which can aggravate rheumatoid arthritis, leukoplakia oral ulcers, uveitis, polymyositis and immune liver disease ALT, AST, CK and other liver enzymes muscle enzyme titers are significantly elevated. Adult Steele's disease fever is difficult to decline.

4. two polysaccharides isolated from Astragalus polysaccharide, Astragalus polysaccharide-Ⅰ and Astragalus polysaccharide-Ⅱ, both caused a significant decrease in the activity of alkaline ribonuclease (RNase) in liver and spleen cells, resulting in the accumulation of RNA content in tissues, thus reducing RNA anabolism.

Pharmacological Effect of Astragalus Polysacharin Powder:

Astragalus Polysacharin is sweet in taste and warm in nature. Efficacy: Tonifying the middle and benefiting the qi, raising the yang and fixing the surface, supporting the toxin and generating muscle, promoting water retention and reducing swelling. It is used for treating weakness of Qi, tiredness and weakness, sinking of the middle energy, sagging of internal organs; spontaneous sweating due to deficiency of the surface; sores and ulcers with insufficient Qi and blood, with pus not festering or not converging for a long time; and edema of the face.

Astragalus as well as astragalus polysaccharide and astragaloside I can enhance and regulate immune function.

(1) on immune organs effect of astragalus polysaccharide by injection, can make the mouse spleen significantly heavier, and significantly antagonize the atrophy of the mouse spleen, thymus, lymph nodes, etc. caused by methylhydrogenated prednisone (prednisolone).

(2) Effects on macrophages and leukocytes Astragalus membranaceus aqueous decoction instilled in mice significantly promoted the number and activated phagocytic activity of liver, spleen, lung and abdominal macrophages and induced the production of interleukin-1 (IL-1). Intraperitoneal injection of Astragalus can significantly prevent and control the decrease of peripheral leukocyte count and bone marrow megakaryocyte count in rats caused by cyclophosphamide.

(3) Enhancement of T cell effect Astragalus polysaccharide can promote the differentiation and maturation of T lymphocytes and significantly increase their activity, resulting in an increase in the percentage of T cells in the thymus and an enhancement of the function of T cell subsets and helper T cells. It also completely antagonized the inhibition of the function of T cell subsets and helper T cells by methylhydrogenated prednisone (prednisolone) or cyclophosphamide. Astragalus has a biphasic regulatory effect on T cells, reducing the inhibitory activity of suppressor T cells (Ts) and enhancing the cellular activity of helper T cells (Th).

(4) Enhance the effect of induced interferon Astragalus aqueous decoction can induce γ-interferon, which has obvious antiviral activity, and promote L9290 tumor-induced interferon in mice. Treatment of cold patients with Astragalus membranaceus showed a significant increase in the ability of peripheral blood leukocytes to induce interferon in response to viruses. Viral myocarditis treated with Astragalus saw a significant increase in α- and γ-interferon. Astragalus and interferon have a synergistic effect on promoting NK cell activity. Astragalus polysaccharide can activate the interferon system and induce interferon in lymphocytes.

(5) Enhancement of humoral immunity Astragalus can promote the proliferation of B cells and the production of immunoglobulins. Astragalus can significantly promote the amount of normal organism-specific antibody production, and infusion can promote IgG production in mice. Normal people taking Astragalus can significantly increase the content of IgM and IgE. Cold patients can significantly increase the content of IgG and IgA in the nasal secretion. Astragalus can increase high IgG in patients with spleen deficiency, but it can also reduce high IgG in patients with hepatitis and nephritis to the normal range, suggesting a regulatory effect on antibodies.