Supply Silybin raw Materials Powder Silybin

CAS:22888-70-6

MF:C25H22O10

MW:482.44

EINECS:245-302-5

Specification​: 99% min Silybin Powder

Sample:Silybin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:light yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Silybin Powder Usage and Synthesis.

Silybin can make liver injury model animals have the characteristics of resistance to hepatotoxic substances, and can restrict the entry of alpha-amanicin (hepatotoxic substances) into cells; It has antioxidant activity; It can normalize phospholipid metabolism by promoting protein synthesis in damaged hepatocytes. It can induce the activity of RNA polymerase I in the nucleus.

After absorption through the digestive tract, silybin is mainly excreted with bile (more than 80% of the total absorbed). Silybin is helpful for stabilizing liver cells, protecting liver, and excreting liver toxins. It also has pharmacological effects such as improving cognitive impairment, protecting brain ischemia-reperfusion injury, and reducing pulmonary hypertension.

Uses of Silybin.

Silybin can stabilize the liver cell membrane, protect the enzyme system of liver cells, clear the freedom of reactive oxygen species in liver cells, thereby improving the detoxification ability of liver cells, and avoid the damage of liver cells under the condition of long-term contact with poisons, taking hepatotoxic drugs, smoking, drinking, etc.

In vitro study of Silybin.

Silybin is a mixture of the approximately equal molar ratio of the enantiomers silibininA and silybininB. Both in vitro and animal studies have shown that silybin has a hepatoprotective effect (anti-hepatotoxicity), protecting liver cells from toxin damage. In in vitro trials, silybin has anticancer effects on human prostate cancer cells, estrogen-dependent and non-dependent human breast cancer cells, human cervical cancer cells, human colon cancer cells, and small and non-small human lung cancer cells.

Product Method of Bulk Silybin Powder.